F892-0509 Screening compound: N-[5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-methylthiophen-3-yl]-2-(1H-indol-3-yl)acetamide

F892-0509 Screening compound: N-[5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-methylthiophen-3-yl]-2-(1H-indol-3-yl)acetamide
F892-0509 Screening compound: N-[5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-methylthiophen-3-yl]-2-(1H-indol-3-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F892-0509
N-[5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-methylthiophen-3-yl]-2-(1H-indol-3-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F892-0509

Molecular Formula

C20H18N4O2S (C20 H18 N4 O2 S)

Compound Name

N-[5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-methylthiophen-3-yl]-2-(1H-indol-3-yl)acetamide

IUPAC name

N-[5-(5-cyclopropyl-124-oxadiazol-3-yl)-2-methylthiophen-3-yl]-2-(1H-indol-3-yl)acetamide

SMILES

Cc(sc(-c1noc(C2CC2)n1)c1)c1NC(Cc1c[nH]c2c1cccc2)=O

InChI

InChI=1S/C20H18N4O2S/c1-11-16(9-17(27-11)19-23-20(26-24-19)12-6-7-12)22-18(25)8-13-10-21-15-5-3-2-4-14(13)15/h2-5,9-10,12,21H,6-8H2,1H3,(H,22,25)

InChI Key

GJSQUOKEQYXLQC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27202319

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

378.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.606

Distribution Coefficient, logD

4.606

Water Solubility, LogSw

-4.34

Polar Surface Area

65.237

Acid Dissociation Constant (pKa)

12.41

Base Dissociation Constant (pKb)

-0.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

F892-0509 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with F892-0509 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F892-0509?
Check Price and Availability of F892-0509, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F892-0509 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F892-0509
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F892-0509
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F892-0509 available by request