F894-0499 Screening compound: N-cyclopropyl-1-{[5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methylthiophen-3-yl]sulfonyl}piperidine-3-carboxamide

F894-0499 Screening compound: N-cyclopropyl-1-{[5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methylthiophen-3-yl]sulfonyl}piperidine-3-carboxamide
F894-0499 Screening compound: N-cyclopropyl-1-{[5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methylthiophen-3-yl]sulfonyl}piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F894-0499
N-cyclopropyl-1-{[5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methylthiophen-3-yl]sulfonyl}piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F894-0499

Molecular Formula

C18H24N4O4S2 (C18 H24 N4 O4 S2)

Compound Name

N-cyclopropyl-1-{[5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methylthiophen-3-yl]sulfonyl}piperidine-3-carboxamide

IUPAC name

N-cyclopropyl-1-{[5-(5-ethyl-124-oxadiazol-3-yl)-2-methylthiophen-3-yl]sulfonyl}piperidine-3-carboxamide

SMILES

CCc1nc(-c2cc(S(N(CCC3)CC3C(NC3CC3)=O)(=O)=O)c(C)s2)no1

InChI

InChI=1S/C18H24N4O4S2/c1-3-16-20-17(21-26-16)14-9-15(11(2)27-14)28(24,25)22-8-4-5-12(10-22)18(23)19-13-6-7-13/h9,12-13H,3-8,10H2,1-2H3,(H,19,23)/t12-/m0/s1

InChI Key

TVPGJJSECJXSGX-LBPRGKRZSA-N

MDL Number (MFCD)

MFCD27202523

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

424.55

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.559

Distribution Coefficient, logD

2.559

Water Solubility, LogSw

-2.68

Polar Surface Area

88.714

Acid Dissociation Constant (pKa)

12.58

Base Dissociation Constant (pKb)

-1.19

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

61.10

F894-0499 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Targeted Diversity Library (40567 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with F894-0499 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F894-0499?
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What is the minimum amount of F894-0499 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F894-0499
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F894-0499
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F894-0499 available by request