F919-0378 Screening compound: N-butyl-3-(5-chloro-2-methoxybenzenesulfonamido)-N-ethyl-4-(piperazin-1-yl)benzamide

F919-0378 Screening compound: N-butyl-3-(5-chloro-2-methoxybenzenesulfonamido)-N-ethyl-4-(piperazin-1-yl)benzamide
F919-0378 Screening compound: N-butyl-3-(5-chloro-2-methoxybenzenesulfonamido)-N-ethyl-4-(piperazin-1-yl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F919-0378
N-butyl-3-(5-chloro-2-methoxybenzenesulfonamido)-N-ethyl-4-(piperazin-1-yl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F919-0378

Molecular Formula

C24H33ClN4O4S (C24 H33 ClN4 O4 S)

Compound Name

N-butyl-3-(5-chloro-2-methoxybenzenesulfonamido)-N-ethyl-4-(piperazin-1-yl)benzamide

IUPAC name

N-butyl-3-(5-chloro-2-methoxybenzenesulfonamido)-N-ethyl-4-(piperazin-1-yl)benzamide

SMILES

CCCCN(CC)C(c(cc1)cc(NS(c(cc(cc2)Cl)c2OC)(=O)=O)c1N1CCNCC1)=O

InChI

InChI=1S/C24H33ClN4O4S/c1-4-6-13-28(5-2)24(30)18-7-9-21(29-14-11-26-12-15-29)20(16-18)27-34(31,32)23-17-19(25)8-10-22(23)33-3/h7-10,16-17,26-27H,4-6,11-15H2,1-3H3

InChI Key

XRVWPYKHANETNM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14971794

Chemical and Physical Properties

Saltdata

CF3COOH

Molecular Weight

509.07

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.477

Distribution Coefficient, logD

3.477

Water Solubility, LogSw

-3.96

Polar Surface Area

79.119

Acid Dissociation Constant (pKa)

6.30

Base Dissociation Constant (pKb)

8.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.80

F919-0378 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F919-0378 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F919-0378?
Check Price and Availability of F919-0378, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F919-0378 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F919-0378
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F919-0378
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F919-0378 available by request