F936-0188 Screening compound: N-[2-(1-methyl-1,2,3,4-tetrahydroquinolin-6-yl)-2-(morpholin-4-yl)ethyl]-[1,1'-biphenyl]-4-carboxamide

F936-0188 Screening compound: N-[2-(1-methyl-1,2,3,4-tetrahydroquinolin-6-yl)-2-(morpholin-4-yl)ethyl]-[1,1'-biphenyl]-4-carboxamide
F936-0188 Screening compound: N-[2-(1-methyl-1,2,3,4-tetrahydroquinolin-6-yl)-2-(morpholin-4-yl)ethyl]-[1,1'-biphenyl]-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F936-0188
N-[2-(1-methyl-1,2,3,4-tetrahydroquinolin-6-yl)-2-(morpholin-4-yl)ethyl]-[1,1'-biphenyl]-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F936-0188

Molecular Formula

C29H33N3O2 (C29 H33 N3 O2)

Compound Name

N-[2-(1-methyl-1,2,3,4-tetrahydroquinolin-6-yl)-2-(morpholin-4-yl)ethyl]-[1,1'-biphenyl]-4-carboxamide

IUPAC name

N-[2-(1-methyl-1234-tetrahydroquinolin-6-yl)-2-(morpholin-4-yl)ethyl]-[11'-biphenyl]-4-carboxamide

SMILES

CN(CCC1)c2c1cc(C(CNC(c(cc1)ccc1-c1ccccc1)=O)N1CCOCC1)cc2

InChI

InChI=1S/C29H33N3O2/c1-31-15-5-8-25-20-26(13-14-27(25)31)28(32-16-18-34-19-17-32)21-30-29(33)24-11-9-23(10-12-24)22-6-3-2-4-7-22/h2-4,6-7,9-14,20,28H,5,8,15-19,21H2,1H3,(H,30,33)/t28-/m0/s1

InChI Key

COTZDLVUJBPQLS-NDEPHWFRSA-N

MDL Number (MFCD)

MFCD08945921

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

455.6

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.958

Distribution Coefficient, logD

3.932

Water Solubility, LogSw

-4.07

Polar Surface Area

37.828

Acid Dissociation Constant (pKa)

11.83

Base Dissociation Constant (pKb)

6.17

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

34.50

F936-0188 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Nervous system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • GPCR
  • Ion Channels
  • Phosphatases

References: we are preparing a list of scientific research reports with F936-0188 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F936-0188?
Check Price and Availability of F936-0188, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F936-0188 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F936-0188
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F936-0188
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F936-0188 available by request