F937-1241 Screening compound: N-[(4-methoxyphenyl)methyl]-4-methyl-2-[4-(trifluoromethyl)phenyl]pyrimidine-5-carboxamide

F937-1241 Screening compound: N-[(4-methoxyphenyl)methyl]-4-methyl-2-[4-(trifluoromethyl)phenyl]pyrimidine-5-carboxamide
F937-1241 Screening compound: N-[(4-methoxyphenyl)methyl]-4-methyl-2-[4-(trifluoromethyl)phenyl]pyrimidine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F937-1241
N-[(4-methoxyphenyl)methyl]-4-methyl-2-[4-(trifluoromethyl)phenyl]pyrimidine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F937-1241

Molecular Formula

C21H18F3N3O2 (C21 H18 F3 N3 O2)

Compound Name

N-[(4-methoxyphenyl)methyl]-4-methyl-2-[4-(trifluoromethyl)phenyl]pyrimidine-5-carboxamide

IUPAC name

N-[(4-methoxyphenyl)methyl]-4-methyl-2-[4-(trifluoromethyl)phenyl]pyrimidine-5-carboxamide

SMILES

Cc(nc(-c1ccc(C(F)(F)F)cc1)nc1)c1C(NCc(cc1)ccc1OC)=O

InChI

InChI=1S/C21H18F3N3O2/c1-13-18(20(28)26-11-14-3-9-17(29-2)10-4-14)12-25-19(27-13)15-5-7-16(8-6-15)21(22,23)24/h3-10,12H,11H2,1-2H3,(H,26,28)

InChI Key

KODCVPJDJNOGPN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27204945

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

401.39

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.557

Distribution Coefficient, logD

4.557

Water Solubility, LogSw

-4.31

Polar Surface Area

51.594

Acid Dissociation Constant (pKa)

11.57

Base Dissociation Constant (pKb)

2.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.05

F937-1241 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with F937-1241 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F937-1241?
Check Price and Availability of F937-1241, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F937-1241 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F937-1241
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F937-1241
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F937-1241 available by request