F937-1365 Screening compound: 4-methyl-N-[2-(pyrrolidin-1-yl)ethyl]-2-[4-(trifluoromethyl)phenyl]pyrimidine-5-carboxamide

F937-1365 Screening compound: 4-methyl-N-[2-(pyrrolidin-1-yl)ethyl]-2-[4-(trifluoromethyl)phenyl]pyrimidine-5-carboxamide
F937-1365 Screening compound: 4-methyl-N-[2-(pyrrolidin-1-yl)ethyl]-2-[4-(trifluoromethyl)phenyl]pyrimidine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F937-1365
4-methyl-N-[2-(pyrrolidin-1-yl)ethyl]-2-[4-(trifluoromethyl)phenyl]pyrimidine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F937-1365

Molecular Formula

C19H21F3N4O (C19 H21 F3 N4 O)

Compound Name

4-methyl-N-[2-(pyrrolidin-1-yl)ethyl]-2-[4-(trifluoromethyl)phenyl]pyrimidine-5-carboxamide

IUPAC name

4-methyl-N-[2-(pyrrolidin-1-yl)ethyl]-2-[4-(trifluoromethyl)phenyl]pyrimidine-5-carboxamide

SMILES

Cc(nc(-c1ccc(C(F)(F)F)cc1)nc1)c1C(NCCN1CCCC1)=O

InChI

InChI=1S/C19H21F3N4O/c1-13-16(18(27)23-8-11-26-9-2-3-10-26)12-24-17(25-13)14-4-6-15(7-5-14)19(20,21)22/h4-7,12H,2-3,8-11H2,1H3,(H,23,27)

InChI Key

JWLVENCKQZGDKA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27204991

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

378.4

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.390

Distribution Coefficient, logD

1.982

Water Solubility, LogSw

-3.57

Polar Surface Area

48.240

Acid Dissociation Constant (pKa)

11.35

Base Dissociation Constant (pKb)

8.79

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.10

F937-1365 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Soluble Diversity Library (15920 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
Targets:
  • GPCR
  • Ion Channels
Agro:
  • Agro

References: we are preparing a list of scientific research reports with F937-1365 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F937-1365?
Check Price and Availability of F937-1365, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F937-1365 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F937-1365
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F937-1365
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F937-1365 available by request