F944-1147 Screening compound: 4-[5-acetamido-4-(4-fluorophenyl)-3-methyl-1H-pyrazol-1-yl]-N-(4-methyl-1,3-thiazol-2-yl)benzamide

F944-1147 Screening compound: 4-[5-acetamido-4-(4-fluorophenyl)-3-methyl-1H-pyrazol-1-yl]-N-(4-methyl-1,3-thiazol-2-yl)benzamide
F944-1147 Screening compound: 4-[5-acetamido-4-(4-fluorophenyl)-3-methyl-1H-pyrazol-1-yl]-N-(4-methyl-1,3-thiazol-2-yl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F944-1147
4-[5-acetamido-4-(4-fluorophenyl)-3-methyl-1H-pyrazol-1-yl]-N-(4-methyl-1,3-thiazol-2-yl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F944-1147

Molecular Formula

C23H20FN5O2S (C23 H20 FN5 O2 S)

Compound Name

4-[5-acetamido-4-(4-fluorophenyl)-3-methyl-1H-pyrazol-1-yl]-N-(4-methyl-1,3-thiazol-2-yl)benzamide

IUPAC name

4-[5-acetamido-4-(4-fluorophenyl)-3-methyl-1H-pyrazol-1-yl]-N-(4-methyl-13-thiazol-2-yl)benzamide

SMILES

CC(Nc(n(-c(cc1)ccc1C(Nc1nc(C)cs1)=O)nc1C)c1-c(cc1)ccc1F)=O

InChI

InChI=1S/C23H20FN5O2S/c1-13-12-32-23(25-13)27-22(31)17-6-10-19(11-7-17)29-21(26-15(3)30)20(14(2)28-29)16-4-8-18(24)9-5-16/h4-12H,1-3H3,(H,26,30)(H,25,27,31)

InChI Key

UQPVVKFRRPQMBC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14973405

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

449.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.525

Distribution Coefficient, logD

3.252

Water Solubility, LogSw

-4.02

Polar Surface Area

70.263

Acid Dissociation Constant (pKa)

7.46

Base Dissociation Constant (pKb)

1.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

F944-1147 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Proteases
  • Kinases

References: we are preparing a list of scientific research reports with F944-1147 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F944-1147?
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What is the minimum amount of F944-1147 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F944-1147
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F944-1147
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F944-1147 available by request