F946-0505 Screening compound: 2-(3,5-dimethyl-1,2-oxazol-4-yl)-6-{4-methoxy-3-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-2,3-dihydropyridazin-3-one

F946-0505 Screening compound: 2-(3,5-dimethyl-1,2-oxazol-4-yl)-6-{4-methoxy-3-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-2,3-dihydropyridazin-3-one
F946-0505 Screening compound: 2-(3,5-dimethyl-1,2-oxazol-4-yl)-6-{4-methoxy-3-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-2,3-dihydropyridazin-3-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F946-0505
2-(3,5-dimethyl-1,2-oxazol-4-yl)-6-{4-methoxy-3-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-2,3-dihydropyridazin-3-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F946-0505

Molecular Formula

C21H25N5O5S (C21 H25 N5 O5 S)

Compound Name

2-(3,5-dimethyl-1,2-oxazol-4-yl)-6-{4-methoxy-3-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-2,3-dihydropyridazin-3-one

IUPAC name

2-(35-dimethyl-12-oxazol-4-yl)-6-{4-methoxy-3-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-23-dihydropyridazin-3-one

SMILES

Cc1noc(C)c1N(C(C=C1)=O)N=C1c(cc1)cc(S(N2CCN(C)CC2)(=O)=O)c1OC

InChI

InChI=1S/C21H25N5O5S/c1-14-21(15(2)31-23-14)26-20(27)8-6-17(22-26)16-5-7-18(30-4)19(13-16)32(28,29)25-11-9-24(3)10-12-25/h5-8,13H,9-12H2,1-4H3

InChI Key

VEBMHSGDFRYZBS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27205557

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

459.53

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.355

Distribution Coefficient, logD

1.292

Water Solubility, LogSw

-2.43

Polar Surface Area

91.383

Acid Dissociation Constant (pKa)

28.13

Base Dissociation Constant (pKb)

6.59

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

F946-0505 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F946-0505 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F946-0505?
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What is the minimum amount of F946-0505 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F946-0505
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F946-0505
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F946-0505 available by request