F949-0127 Screening compound: 2-(3,4-diethoxyphenyl)-1-[5-(5-methyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-indol-1-yl]ethan-1-one

F949-0127 Screening compound: 2-(3,4-diethoxyphenyl)-1-[5-(5-methyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-indol-1-yl]ethan-1-one
F949-0127 Screening compound: 2-(3,4-diethoxyphenyl)-1-[5-(5-methyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-indol-1-yl]ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F949-0127
2-(3,4-diethoxyphenyl)-1-[5-(5-methyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-indol-1-yl]ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F949-0127

Molecular Formula

C23H25N3O4 (C23 H25 N3 O4)

Compound Name

2-(3,4-diethoxyphenyl)-1-[5-(5-methyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-indol-1-yl]ethan-1-one

IUPAC name

2-(34-diethoxyphenyl)-1-[5-(5-methyl-124-oxadiazol-3-yl)-23-dihydro-1H-indol-1-yl]ethan-1-one

SMILES

CCOc(ccc(CC(N(CC1)c(cc2)c1cc2-c1noc(C)n1)=O)c1)c1OCC

InChI

InChI=1S/C23H25N3O4/c1-4-28-20-9-6-16(12-21(20)29-5-2)13-22(27)26-11-10-17-14-18(7-8-19(17)26)23-24-15(3)30-25-23/h6-9,12,14H,4-5,10-11,13H2,1-3H3

InChI Key

GWQCQIRVQWXXDC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27205609

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

407.47

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.019

Distribution Coefficient, logD

4.019

Water Solubility, LogSw

-4.14

Polar Surface Area

60.716

Acid Dissociation Constant (pKa)

16.37

Base Dissociation Constant (pKb)

-1.73

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.80

F949-0127 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Anti-HIV1 Library (19540 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
  • Cancer
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with F949-0127 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F949-0127?
Check Price and Availability of F949-0127, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F949-0127 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F949-0127
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F949-0127
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F949-0127 available by request