F949-0160 Screening compound: 3-[5-(5-ETHYL-1,2,4-OXADIAZOL-3-YL)-2,3-DIHYDRO-1H-INDOLE-1-CARBONYL]-2H-CHROMEN-2-ONE

F949-0160 Screening compound: 3-[5-(5-ETHYL-1,2,4-OXADIAZOL-3-YL)-2,3-DIHYDRO-1H-INDOLE-1-CARBONYL]-2H-CHROMEN-2-ONE
F949-0160 Screening compound: 3-[5-(5-ETHYL-1,2,4-OXADIAZOL-3-YL)-2,3-DIHYDRO-1H-INDOLE-1-CARBONYL]-2H-CHROMEN-2-ONE alternative view

Chemical Structure Depiction of ChemDiv screening compound F949-0160
3-[5-(5-ETHYL-1,2,4-OXADIAZOL-3-YL)-2,3-DIHYDRO-1H-INDOLE-1-CARBONYL]-2H-CHROMEN-2-ONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F949-0160

Molecular Formula

C22H17N3O4 (C22 H17 N3 O4)

Compound Name

3-[5-(5-ETHYL-1,2,4-OXADIAZOL-3-YL)-2,3-DIHYDRO-1H-INDOLE-1-CARBONYL]-2H-CHROMEN-2-ONE

IUPAC name

n/a

SMILES

CCc1nc(-c(cc2)cc(CC3)c2N3C(C2=Cc(cccc3)c3OC2=O)=O)no1

InChI

InChI=1S/C22H17N3O4/c1-2-19-23-20(24-29-19)15-7-8-17-13(11-15)9-10-25(17)21(26)16-12-14-5-3-4-6-18(14)28-22(16)27/h3-8,11-12H,2,9-10H2,1H3

InChI Key

LXDFRTQDEZKGFH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14973472

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

387.39

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.994

Distribution Coefficient, logD

3.994

Water Solubility, LogSw

-4.18

Polar Surface Area

68.182

Acid Dissociation Constant (pKa)

25.12

Base Dissociation Constant (pKb)

-2.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

F949-0160 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with F949-0160 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F949-0160?
Check Price and Availability of F949-0160, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F949-0160 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F949-0160
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F949-0160
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F949-0160 available by request