F951-0853 Screening compound: 1-cyclopropanecarbonyl-5-[4-(3-methoxyphenyl)piperazine-1-carbonyl]-2,3-dihydro-1H-indole

F951-0853 Screening compound: 1-cyclopropanecarbonyl-5-[4-(3-methoxyphenyl)piperazine-1-carbonyl]-2,3-dihydro-1H-indole
F951-0853 Screening compound: 1-cyclopropanecarbonyl-5-[4-(3-methoxyphenyl)piperazine-1-carbonyl]-2,3-dihydro-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound F951-0853
1-cyclopropanecarbonyl-5-[4-(3-methoxyphenyl)piperazine-1-carbonyl]-2,3-dihydro-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F951-0853

Molecular Formula

C24H27N3O3 (C24 H27 N3 O3)

Compound Name

1-cyclopropanecarbonyl-5-[4-(3-methoxyphenyl)piperazine-1-carbonyl]-2,3-dihydro-1H-indole

IUPAC name

1-cyclopropanecarbonyl-5-[4-(3-methoxyphenyl)piperazine-1-carbonyl]-23-dihydro-1H-indole

SMILES

COc1cccc(N(CC2)CCN2C(c(cc2)cc(CC3)c2N3C(C2CC2)=O)=O)c1

InChI

InChI=1S/C24H27N3O3/c1-30-21-4-2-3-20(16-21)25-11-13-26(14-12-25)23(28)19-7-8-22-18(15-19)9-10-27(22)24(29)17-5-6-17/h2-4,7-8,15-17H,5-6,9-14H2,1H3

InChI Key

XGKLEUPYNHQEDI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27205739

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

405.5

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.057

Distribution Coefficient, logD

3.057

Water Solubility, LogSw

-3.39

Polar Surface Area

43.893

Acid Dissociation Constant (pKa)

21.07

Base Dissociation Constant (pKb)

2.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

F951-0853 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with F951-0853 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F951-0853?
Check Price and Availability of F951-0853, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F951-0853 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F951-0853
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F951-0853
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F951-0853 available by request