G008-2947 Screening compound: 3-[5-(PYRROLIDINE-1-SULFONYL)THIOPHEN-2-YL]-5-(TRIFLUOROMETHYL)-1,2-OXAZOLE

G008-2947 Screening compound: 3-[5-(PYRROLIDINE-1-SULFONYL)THIOPHEN-2-YL]-5-(TRIFLUOROMETHYL)-1,2-OXAZOLE
G008-2947 Screening compound: 3-[5-(PYRROLIDINE-1-SULFONYL)THIOPHEN-2-YL]-5-(TRIFLUOROMETHYL)-1,2-OXAZOLE alternative view

Chemical Structure Depiction of ChemDiv screening compound G008-2947
3-[5-(PYRROLIDINE-1-SULFONYL)THIOPHEN-2-YL]-5-(TRIFLUOROMETHYL)-1,2-OXAZOLE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G008-2947

Molecular Formula

C12H11F3N2O3S2 (C12 H11 F3 N2 O3 S2)

Compound Name

3-[5-(PYRROLIDINE-1-SULFONYL)THIOPHEN-2-YL]-5-(TRIFLUOROMETHYL)-1,2-OXAZOLE

IUPAC name

3-[5-(pyrrolidine-1-sulfonyl)thiophen-2-yl]-5-(trifluoromethyl)-12-oxazole

SMILES

O=S(c1ccc(-c2noc(C(F)(F)F)c2)s1)(N1CCCC1)=O

InChI

InChI=1S/C12H11F3N2O3S2/c13-12(14,15)10-7-8(16-20-10)9-3-4-11(21-9)22(18,19)17-5-1-2-6-17/h3-4,7H,1-2,5-6H2

InChI Key

ZBCTXMYSPXEDKT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00662156

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

352.36

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.329

Distribution Coefficient, logD

3.329

Water Solubility, LogSw

-3.57

Polar Surface Area

54.869

Acid Dissociation Constant (pKa)

27.94

Base Dissociation Constant (pKb)

-4.93

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

G008-2947 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Anticancer Library (62698 compounds)

Antiparasite Library (23996 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Dark Chemical Matter Library (18430 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Akt-Targeted Library (14764 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

New Agro Library (44492 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Pool
Therapeutical areas:
  • Cancer
  • Infections
  • Immune system
  • animal
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Agro:
  • Agro
  • Agro
Targets:
  • Others
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G008-2947 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G008-2947?
Check Price and Availability of G008-2947, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G008-2947 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G008-2947
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G008-2947
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G008-2947 available by request