G008-3019 Screening compound: 8-({5-[5-(trifluoromethyl)-1,2-oxazol-3-yl]thiophen-2-yl}sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane

G008-3019 Screening compound: 8-({5-[5-(trifluoromethyl)-1,2-oxazol-3-yl]thiophen-2-yl}sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane
G008-3019 Screening compound: 8-({5-[5-(trifluoromethyl)-1,2-oxazol-3-yl]thiophen-2-yl}sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound G008-3019
8-({5-[5-(trifluoromethyl)-1,2-oxazol-3-yl]thiophen-2-yl}sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G008-3019

Molecular Formula

C15H15F3N2O5S2 (C15 H15 F3 N2 O5 S2)

Compound Name

8-({5-[5-(trifluoromethyl)-1,2-oxazol-3-yl]thiophen-2-yl}sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane

IUPAC name

8-({5-[5-(trifluoromethyl)-12-oxazol-3-yl]thiophen-2-yl}sulfonyl)-14-dioxa-8-azaspiro[4.5]decane

SMILES

O=S(c1ccc(-c2noc(C(F)(F)F)c2)s1)(N(CC1)CCC11OCCO1)=O

InChI

InChI=1S/C15H15F3N2O5S2/c16-15(17,18)12-9-10(19-25-12)11-1-2-13(26-11)27(21,22)20-5-3-14(4-6-20)23-7-8-24-14/h1-2,9H,3-8H2

InChI Key

APXPLSLTSVZMOS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14975597

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

424.42

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.074

Distribution Coefficient, logD

3.074

Water Solubility, LogSw

-3.32

Polar Surface Area

68.940

Acid Dissociation Constant (pKa)

27.46

Base Dissociation Constant (pKb)

-6.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

53.30

G008-3019 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Akt-Targeted Library (14764 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Others
  • Kinases
Mechanism of action:
  • Epigenetic
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G008-3019 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G008-3019?
Check Price and Availability of G008-3019, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G008-3019 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G008-3019
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G008-3019
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G008-3019 available by request