G011-0143 Screening compound: 2-[3-methyl-1-(3-methylphenyl)-5-(1H-pyrrol-1-yl)-1H-pyrazole-4-carbonyl]-1,2,3,4-tetrahydroisoquinoline

G011-0143 Screening compound: 2-[3-methyl-1-(3-methylphenyl)-5-(1H-pyrrol-1-yl)-1H-pyrazole-4-carbonyl]-1,2,3,4-tetrahydroisoquinoline
G011-0143 Screening compound: 2-[3-methyl-1-(3-methylphenyl)-5-(1H-pyrrol-1-yl)-1H-pyrazole-4-carbonyl]-1,2,3,4-tetrahydroisoquinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound G011-0143
2-[3-methyl-1-(3-methylphenyl)-5-(1H-pyrrol-1-yl)-1H-pyrazole-4-carbonyl]-1,2,3,4-tetrahydroisoquinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G011-0143

Molecular Formula

C25H24N4O (C25 H24 N4 O)

Compound Name

2-[3-methyl-1-(3-methylphenyl)-5-(1H-pyrrol-1-yl)-1H-pyrazole-4-carbonyl]-1,2,3,4-tetrahydroisoquinoline

IUPAC name

2-[3-methyl-1-(3-methylphenyl)-5-(1H-pyrrol-1-yl)-1H-pyrazole-4-carbonyl]-1234-tetrahydroisoquinoline

SMILES

Cc(c(C(N(CC1)Cc2c1cccc2)=O)c1-n2cccc2)nn1-c1cc(C)ccc1

InChI

InChI=1S/C25H24N4O/c1-18-8-7-11-22(16-18)29-24(27-13-5-6-14-27)23(19(2)26-29)25(30)28-15-12-20-9-3-4-10-21(20)17-28/h3-11,13-14,16H,12,15,17H2,1-2H3

InChI Key

QKZCZLHEVZQOQK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14976359

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

396.49

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.781

Distribution Coefficient, logD

4.781

Water Solubility, LogSw

-4.65

Polar Surface Area

33.758

Acid Dissociation Constant (pKa)

24.26

Base Dissociation Constant (pKb)

2.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

G011-0143 in Drug Discovery

Included in Screening Libraries

Cardiovascular Library (22201 compounds)

SH2 Library (10483 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Cancer
  • Endocrine
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G011-0143 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G011-0143?
Check Price and Availability of G011-0143, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G011-0143 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G011-0143
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G011-0143
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G011-0143 available by request