G012-0483 Screening compound: 1-(2,5-dimethylphenyl)-3-propyltetrahydro-5lambda~6~-thieno[3,4-d]imidazole-2,5,5(1H,3H)-trione

G012-0483 Screening compound: 1-(2,5-dimethylphenyl)-3-propyltetrahydro-5lambda~6~-thieno[3,4-d]imidazole-2,5,5(1H,3H)-trione
G012-0483 Screening compound: 1-(2,5-dimethylphenyl)-3-propyltetrahydro-5lambda~6~-thieno[3,4-d]imidazole-2,5,5(1H,3H)-trione alternative view

Chemical Structure Depiction of ChemDiv screening compound G012-0483
1-(2,5-dimethylphenyl)-3-propyltetrahydro-5lambda~6~-thieno[3,4-d]imidazole-2,5,5(1H,3H)-trione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G012-0483

Molecular Formula

C16H22N2O3S (C16 H22 N2 O3 S)

Compound Name

1-(2,5-dimethylphenyl)-3-propyltetrahydro-5lambda~6~-thieno[3,4-d]imidazole-2,5,5(1H,3H)-trione

IUPAC name

1-(25-dimethylphenyl)-3-propyl-hexahydro-1H-5lambda6-thieno[34-d]imidazole-255-trione

SMILES

CCCN(C(CS(C1)(=O)=O)C1N1c2c(C)ccc(C)c2)C1=O

InChI

InChI=1S/C16H22N2O3S/c1-4-7-17-14-9-22(20,21)10-15(14)18(16(17)19)13-8-11(2)5-6-12(13)3/h5-6,8,14-15H,4,7,9-10H2,1-3H3

InChI Key

HJWGNAINIIOFJZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08541124

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

322.43

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.341

Distribution Coefficient, logD

2.341

Water Solubility, LogSw

-2.54

Polar Surface Area

46.522

Acid Dissociation Constant (pKa)

19.62

Base Dissociation Constant (pKb)

-5.42

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

56.30

G012-0483 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Cancer
Mechanism of action:
  • Epigenetic
  • PPI modulators

References: we are preparing a list of scientific research reports with G012-0483 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G012-0483?
Check Price and Availability of G012-0483, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G012-0483 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G012-0483
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G012-0483
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G012-0483 available by request