G015-0237 Screening compound: 1-(4-chlorophenyl)-4-{1-[5-(pyrrolidin-1-yl)-1,3,4-thiadiazol-2-yl]-1H-pyrrole-2-carbonyl}piperazine

G015-0237 Screening compound: 1-(4-chlorophenyl)-4-{1-[5-(pyrrolidin-1-yl)-1,3,4-thiadiazol-2-yl]-1H-pyrrole-2-carbonyl}piperazine
G015-0237 Screening compound: 1-(4-chlorophenyl)-4-{1-[5-(pyrrolidin-1-yl)-1,3,4-thiadiazol-2-yl]-1H-pyrrole-2-carbonyl}piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G015-0237
1-(4-chlorophenyl)-4-{1-[5-(pyrrolidin-1-yl)-1,3,4-thiadiazol-2-yl]-1H-pyrrole-2-carbonyl}piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G015-0237

Molecular Formula

C21H23ClN6OS (C21 H23 ClN6 OS)

Compound Name

1-(4-chlorophenyl)-4-{1-[5-(pyrrolidin-1-yl)-1,3,4-thiadiazol-2-yl]-1H-pyrrole-2-carbonyl}piperazine

IUPAC name

1-(4-chlorophenyl)-4-{1-[5-(pyrrolidin-1-yl)-134-thiadiazol-2-yl]-1H-pyrrole-2-carbonyl}piperazine

SMILES

O=C(c1cccn1-c1nnc(N2CCCC2)s1)N(CC1)CCN1c(cc1)ccc1Cl

InChI

InChI=1S/C21H23ClN6OS/c22-16-5-7-17(8-6-16)25-12-14-26(15-13-25)19(29)18-4-3-11-28(18)21-24-23-20(30-21)27-9-1-2-10-27/h3-8,11H,1-2,9-10,12-15H2

InChI Key

RCBQXBMXMPIMGM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14976725

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

442.97

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.495

Distribution Coefficient, logD

4.495

Water Solubility, LogSw

-4.79

Polar Surface Area

49.148

Acid Dissociation Constant (pKa)

22.09

Base Dissociation Constant (pKb)

5.38

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

G015-0237 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antimitotic Tubulin Library (17355 compounds)

Antiviral Annotated Library (21441 compounds)

GPCR Targeted Library (31838 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G015-0237 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G015-0237?
Check Price and Availability of G015-0237, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G015-0237 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G015-0237
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G015-0237
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G015-0237 available by request