G015-1141 Screening compound: 1'-{1-[5-(piperidin-1-yl)-1,3,4-thiadiazol-2-yl]-1H-pyrrole-2-carbonyl}-1,4'-bipiperidine

G015-1141 Screening compound: 1'-{1-[5-(piperidin-1-yl)-1,3,4-thiadiazol-2-yl]-1H-pyrrole-2-carbonyl}-1,4'-bipiperidine
G015-1141 Screening compound: 1'-{1-[5-(piperidin-1-yl)-1,3,4-thiadiazol-2-yl]-1H-pyrrole-2-carbonyl}-1,4'-bipiperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound G015-1141
1'-{1-[5-(piperidin-1-yl)-1,3,4-thiadiazol-2-yl]-1H-pyrrole-2-carbonyl}-1,4'-bipiperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G015-1141

Molecular Formula

C22H32N6OS (C22 H32 N6 OS)

Compound Name

1'-{1-[5-(piperidin-1-yl)-1,3,4-thiadiazol-2-yl]-1H-pyrrole-2-carbonyl}-1,4'-bipiperidine

IUPAC name

1'-{1-[5-(piperidin-1-yl)-134-thiadiazol-2-yl]-1H-pyrrole-2-carbonyl}-14'-bipiperidine

SMILES

O=C(c1cccn1-c1nnc(N2CCCCC2)s1)N(CC1)CCC1N1CCCCC1

InChI

InChI=1S/C22H32N6OS/c29-20(26-16-9-18(10-17-26)25-11-3-1-4-12-25)19-8-7-15-28(19)22-24-23-21(30-22)27-13-5-2-6-14-27/h7-8,15,18H,1-6,9-14,16-17H2

InChI Key

OFEONHLZMLQHFB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14976943

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.6

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.796

Distribution Coefficient, logD

0.356

Water Solubility, LogSw

-3.83

Polar Surface Area

48.615

Acid Dissociation Constant (pKa)

22.87

Base Dissociation Constant (pKb)

10.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

68.18

G015-1141 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G015-1141 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G015-1141?
Check Price and Availability of G015-1141, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G015-1141 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G015-1141
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G015-1141
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G015-1141 available by request