G020-0640 Screening compound: 6-[(4-fluorophenyl)methyl]-2-methyl-5-{[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl}-2H,6H,7H-pyrazolo[4,3-d]pyrimidin-7-one

G020-0640 Screening compound: 6-[(4-fluorophenyl)methyl]-2-methyl-5-{[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl}-2H,6H,7H-pyrazolo[4,3-d]pyrimidin-7-one
G020-0640 Screening compound: 6-[(4-fluorophenyl)methyl]-2-methyl-5-{[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl}-2H,6H,7H-pyrazolo[4,3-d]pyrimidin-7-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G020-0640
6-[(4-fluorophenyl)methyl]-2-methyl-5-{[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl}-2H,6H,7H-pyrazolo[4,3-d]pyrimidin-7-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G020-0640

Molecular Formula

C21H24FN5O2S (C21 H24 FN5 O2 S)

Compound Name

6-[(4-fluorophenyl)methyl]-2-methyl-5-{[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl}-2H,6H,7H-pyrazolo[4,3-d]pyrimidin-7-one

IUPAC name

6-[(4-fluorophenyl)methyl]-2-methyl-5-{[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl}-2H6H7H-pyrazolo[43-d]pyrimidin-7-one

SMILES

CC(CC1)CCN1C(CSC(N1Cc(cc2)ccc2F)=Nc2cn(C)nc2C1=O)=O

InChI

InChI=1S/C21H24FN5O2S/c1-14-7-9-26(10-8-14)18(28)13-30-21-23-17-12-25(2)24-19(17)20(29)27(21)11-15-3-5-16(22)6-4-15/h3-6,12,14H,7-11,13H2,1-2H3

InChI Key

ZGPNMGZNGCPWRG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27209115

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

429.52

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.370

Distribution Coefficient, logD

2.370

Water Solubility, LogSw

-2.41

Polar Surface Area

57.610

Acid Dissociation Constant (pKa)

26.31

Base Dissociation Constant (pKb)

1.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.90

G020-0640 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G020-0640 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G020-0640?
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What is the minimum amount of G020-0640 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G020-0640
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G020-0640
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G020-0640 available by request