G069-0484 Screening compound: 1,3,3-trimethyl-N-({1-[(4-methylphenyl)methyl]piperidin-4-yl}methyl)-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide

G069-0484 Screening compound: 1,3,3-trimethyl-N-({1-[(4-methylphenyl)methyl]piperidin-4-yl}methyl)-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide
G069-0484 Screening compound: 1,3,3-trimethyl-N-({1-[(4-methylphenyl)methyl]piperidin-4-yl}methyl)-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G069-0484
1,3,3-trimethyl-N-({1-[(4-methylphenyl)methyl]piperidin-4-yl}methyl)-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G069-0484

Molecular Formula

C25H33N3O3S (C25 H33 N3 O3 S)

Compound Name

1,3,3-trimethyl-N-({1-[(4-methylphenyl)methyl]piperidin-4-yl}methyl)-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide

IUPAC name

133-trimethyl-N-({1-[(4-methylphenyl)methyl]piperidin-4-yl}methyl)-2-oxo-23-dihydro-1H-indole-5-sulfonamide

SMILES

CC(C)(c(cc(cc1)S(NCC2CCN(Cc3ccc(C)cc3)CC2)(=O)=O)c1N1C)C1=O

InChI

InChI=1S/C25H33N3O3S/c1-18-5-7-20(8-6-18)17-28-13-11-19(12-14-28)16-26-32(30,31)21-9-10-23-22(15-21)25(2,3)24(29)27(23)4/h5-10,15,19,26H,11-14,16-17H2,1-4H3

InChI Key

LOCIBFPCOBRXTB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14978406

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

455.62

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.037

Distribution Coefficient, logD

1.744

Water Solubility, LogSw

-4.12

Polar Surface Area

61.235

Acid Dissociation Constant (pKa)

11.48

Base Dissociation Constant (pKb)

9.69

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

48.00

G069-0484 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • GPCR
  • GPCR
  • Ion Channels
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G069-0484 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G069-0484?
Check Price and Availability of G069-0484, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G069-0484 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G069-0484
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G069-0484
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G069-0484 available by request