G070-0183 Screening compound: ethyl 4-[(4-{[3-(dimethylamino)-4-methylphenyl]carbamoyl}piperidin-1-yl)sulfonyl]-2,5-dimethyl-1H-pyrrole-3-carboxylate

G070-0183 Screening compound: ethyl 4-[(4-{[3-(dimethylamino)-4-methylphenyl]carbamoyl}piperidin-1-yl)sulfonyl]-2,5-dimethyl-1H-pyrrole-3-carboxylate
G070-0183 Screening compound: ethyl 4-[(4-{[3-(dimethylamino)-4-methylphenyl]carbamoyl}piperidin-1-yl)sulfonyl]-2,5-dimethyl-1H-pyrrole-3-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound G070-0183
ethyl 4-[(4-{[3-(dimethylamino)-4-methylphenyl]carbamoyl}piperidin-1-yl)sulfonyl]-2,5-dimethyl-1H-pyrrole-3-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G070-0183

Molecular Formula

C24H34N4O5S (C24 H34 N4 O5 S)

Compound Name

ethyl 4-[(4-{[3-(dimethylamino)-4-methylphenyl]carbamoyl}piperidin-1-yl)sulfonyl]-2,5-dimethyl-1H-pyrrole-3-carboxylate

IUPAC name

ethyl 4-[(4-{[3-(dimethylamino)-4-methylphenyl]carbamoyl}piperidin-1-yl)sulfonyl]-25-dimethyl-1H-pyrrole-3-carboxylate

SMILES

CCOC(c1c(C)[nH]c(C)c1S(N(CC1)CCC1C(Nc1cc(N(C)C)c(C)cc1)=O)(=O)=O)=O

InChI

InChI=1S/C24H34N4O5S/c1-7-33-24(30)21-16(3)25-17(4)22(21)34(31,32)28-12-10-18(11-13-28)23(29)26-19-9-8-15(2)20(14-19)27(5)6/h8-9,14,18,25H,7,10-13H2,1-6H3,(H,26,29)

InChI Key

KCKAEIFFVWTHGZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27209426

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

490.62

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.095

Distribution Coefficient, logD

3.094

Water Solubility, LogSw

-3.36

Polar Surface Area

89.086

Acid Dissociation Constant (pKa)

11.47

Base Dissociation Constant (pKb)

4.14

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

G070-0183 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G070-0183 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G070-0183?
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What is the minimum amount of G070-0183 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G070-0183
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G070-0183
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G070-0183 available by request