G115-0188 Screening compound: methyl 2-[2-methyl-5-(3-methyl-1,2-oxazol-5-yl)benzenesulfonamido]-4-phenylthiophene-3-carboxylate

G115-0188 Screening compound: methyl 2-[2-methyl-5-(3-methyl-1,2-oxazol-5-yl)benzenesulfonamido]-4-phenylthiophene-3-carboxylate
G115-0188 Screening compound: methyl 2-[2-methyl-5-(3-methyl-1,2-oxazol-5-yl)benzenesulfonamido]-4-phenylthiophene-3-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound G115-0188
methyl 2-[2-methyl-5-(3-methyl-1,2-oxazol-5-yl)benzenesulfonamido]-4-phenylthiophene-3-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G115-0188

Molecular Formula

C23H20N2O5S2 (C23 H20 N2 O5 S2)

Compound Name

methyl 2-[2-methyl-5-(3-methyl-1,2-oxazol-5-yl)benzenesulfonamido]-4-phenylthiophene-3-carboxylate

IUPAC name

methyl 2-[2-methyl-5-(3-methyl-12-oxazol-5-yl)benzenesulfonamido]-4-phenylthiophene-3-carboxylate

SMILES

Cc1noc(-c2cc(S(Nc3c(C(OC)=O)c(-c4ccccc4)cs3)(=O)=O)c(C)cc2)c1

InChI

InChI=1S/C23H20N2O5S2/c1-14-9-10-17(19-11-15(2)24-30-19)12-20(14)32(27,28)25-22-21(23(26)29-3)18(13-31-22)16-7-5-4-6-8-16/h4-13,25H,1-3H3

InChI Key

DQDVPBNXLGMQTG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14980788

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

468.55

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.967

Distribution Coefficient, logD

1.541

Water Solubility, LogSw

-4.72

Polar Surface Area

82.926

Acid Dissociation Constant (pKa)

3.97

Base Dissociation Constant (pKb)

-2.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

G115-0188 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with G115-0188 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G115-0188?
Check Price and Availability of G115-0188, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G115-0188 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G115-0188
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G115-0188
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G115-0188 available by request