G119-0269 Screening compound: 5-(4-benzylpiperazine-1-carbonyl)-2,3-dimethyl-1H-indole

G119-0269 Screening compound: 5-(4-benzylpiperazine-1-carbonyl)-2,3-dimethyl-1H-indole
G119-0269 Screening compound: 5-(4-benzylpiperazine-1-carbonyl)-2,3-dimethyl-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound G119-0269
5-(4-benzylpiperazine-1-carbonyl)-2,3-dimethyl-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G119-0269

Molecular Formula

C22H25N3O (C22 H25 N3 O)

Compound Name

5-(4-benzylpiperazine-1-carbonyl)-2,3-dimethyl-1H-indole

IUPAC name

5-(4-benzylpiperazine-1-carbonyl)-23-dimethyl-1H-indole

SMILES

Cc1c(C)[nH]c(cc2)c1cc2C(N1CCN(Cc2ccccc2)CC1)=O

InChI

InChI=1S/C22H25N3O/c1-16-17(2)23-21-9-8-19(14-20(16)21)22(26)25-12-10-24(11-13-25)15-18-6-4-3-5-7-18/h3-9,14,23H,10-13,15H2,1-2H3

InChI Key

HUJIVDCYYHTWFE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07439636

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

347.46

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.113

Distribution Coefficient, logD

3.097

Water Solubility, LogSw

-3.23

Polar Surface Area

30.353

Acid Dissociation Constant (pKa)

17.29

Base Dissociation Constant (pKb)

5.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

G119-0269 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nucleic Acid Ligands (8311 compounds)

Protein-Protein Interaction Library (218420 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
  • Immune system
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G119-0269 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G119-0269?
Check Price and Availability of G119-0269, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G119-0269 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G119-0269
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G119-0269
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G119-0269 available by request