G119-0484 Screening compound: N-{3-[4-(2-fluorophenyl)piperazin-1-yl]propyl}-1,2,3-trimethyl-1H-indole-5-carboxamide

G119-0484 Screening compound: N-{3-[4-(2-fluorophenyl)piperazin-1-yl]propyl}-1,2,3-trimethyl-1H-indole-5-carboxamide
G119-0484 Screening compound: N-{3-[4-(2-fluorophenyl)piperazin-1-yl]propyl}-1,2,3-trimethyl-1H-indole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G119-0484
N-{3-[4-(2-fluorophenyl)piperazin-1-yl]propyl}-1,2,3-trimethyl-1H-indole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G119-0484

Molecular Formula

C25H31FN4O (C25 H31 FN4 O)

Compound Name

N-{3-[4-(2-fluorophenyl)piperazin-1-yl]propyl}-1,2,3-trimethyl-1H-indole-5-carboxamide

IUPAC name

N-{3-[4-(2-fluorophenyl)piperazin-1-yl]propyl}-123-trimethyl-1H-indole-5-carboxamide

SMILES

Cc1c(C)n(C)c(cc2)c1cc2C(NCCCN(CC1)CCN1c(cccc1)c1F)=O

InChI

InChI=1S/C25H31FN4O/c1-18-19(2)28(3)23-10-9-20(17-21(18)23)25(31)27-11-6-12-29-13-15-30(16-14-29)24-8-5-4-7-22(24)26/h4-5,7-10,17H,6,11-16H2,1-3H3,(H,27,31)

InChI Key

MNLJQFJILWSOQS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14981844

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

422.55

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.480

Distribution Coefficient, logD

3.178

Water Solubility, LogSw

-3.90

Polar Surface Area

33.717

Acid Dissociation Constant (pKa)

15.19

Base Dissociation Constant (pKb)

7.40

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

G119-0484 in Drug Discovery

Included in Screening Libraries

Nucleic Acid Ligands (8311 compounds)

Protein-Protein Interaction Library (218420 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
  • Immune system
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G119-0484 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G119-0484?
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What is the minimum amount of G119-0484 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G119-0484
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G119-0484
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G119-0484 available by request