G119-1006 Screening compound: 1-benzyl-2,3-dimethyl-N-[3-(morpholin-4-yl)propyl]-1H-indole-5-carboxamide

G119-1006 Screening compound: 1-benzyl-2,3-dimethyl-N-[3-(morpholin-4-yl)propyl]-1H-indole-5-carboxamide
G119-1006 Screening compound: 1-benzyl-2,3-dimethyl-N-[3-(morpholin-4-yl)propyl]-1H-indole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G119-1006
1-benzyl-2,3-dimethyl-N-[3-(morpholin-4-yl)propyl]-1H-indole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G119-1006

Molecular Formula

C25H31N3O2 (C25 H31 N3 O2)

Compound Name

1-benzyl-2,3-dimethyl-N-[3-(morpholin-4-yl)propyl]-1H-indole-5-carboxamide

IUPAC name

1-benzyl-23-dimethyl-N-[3-(morpholin-4-yl)propyl]-1H-indole-5-carboxamide

SMILES

Cc1c(C)n(Cc2ccccc2)c(cc2)c1cc2C(NCCCN1CCOCC1)=O

InChI

InChI=1S/C25H31N3O2/c1-19-20(2)28(18-21-7-4-3-5-8-21)24-10-9-22(17-23(19)24)25(29)26-11-6-12-27-13-15-30-16-14-27/h3-5,7-10,17H,6,11-16,18H2,1-2H3,(H,26,29)

InChI Key

BRKYBGNMHLZFKM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14981976

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

405.54

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.448

Distribution Coefficient, logD

3.060

Water Solubility, LogSw

-3.64

Polar Surface Area

37.585

Acid Dissociation Constant (pKa)

15.19

Base Dissociation Constant (pKb)

7.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

G119-1006 in Drug Discovery

Included in Screening Libraries

CNS targets activity set (6557 compounds)

Dark Chemical Matter Library (18430 compounds)

GPCR Targeted Library (31838 compounds)

Human GPCR Annotated Library (5539 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Epigenetics Focused Set (26518 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Structure:
  • Pool
Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Immune system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • GPCR
  • Kinases
  • Phosphatases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G119-1006 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G119-1006?
Check Price and Availability of G119-1006, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G119-1006 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G119-1006
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G119-1006
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G119-1006 available by request