G122-1509 Screening compound: (4-benzylpiperazino){5-[3,4-dihydro-1(2H)-quinolinyl]-2-thienyl}methanone

G122-1509 Screening compound: (4-benzylpiperazino){5-[3,4-dihydro-1(2H)-quinolinyl]-2-thienyl}methanone
G122-1509 Screening compound: (4-benzylpiperazino){5-[3,4-dihydro-1(2H)-quinolinyl]-2-thienyl}methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound G122-1509
(4-benzylpiperazino){5-[3,4-dihydro-1(2H)-quinolinyl]-2-thienyl}methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G122-1509

Molecular Formula

C25H27N3OS (C25 H27 N3 OS)

Compound Name

(4-benzylpiperazino){5-[3,4-dihydro-1(2H)-quinolinyl]-2-thienyl}methanone

IUPAC name

1-[5-(4-benzylpiperazine-1-carbonyl)thiophen-2-yl]-1234-tetrahydroquinoline

SMILES

O=C(c1ccc(N(CCC2)c3c2cccc3)s1)N1CCN(Cc2ccccc2)CC1

InChI

InChI=1S/C25H27N3OS/c29-25(27-17-15-26(16-18-27)19-20-7-2-1-3-8-20)23-12-13-24(30-23)28-14-6-10-21-9-4-5-11-22(21)28/h1-5,7-9,11-13H,6,10,14-19H2

InChI Key

GAHRYMVSLQKOCV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14982453

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

417.58

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.051

Distribution Coefficient, logD

5.036

Water Solubility, LogSw

-4.74

Polar Surface Area

23.914

Acid Dissociation Constant (pKa)

24.50

Base Dissociation Constant (pKb)

5.94

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

G122-1509 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
Targets:
  • GPCR
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G122-1509 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G122-1509?
Check Price and Availability of G122-1509, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G122-1509 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G122-1509
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G122-1509
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G122-1509 available by request