G125-0751 Screening compound: 2-methyl-1-{5-[4-(4-methylpiperazine-1-carbonyl)piperidine-1-carbonyl]thiophen-2-yl}-1H-indole

G125-0751 Screening compound: 2-methyl-1-{5-[4-(4-methylpiperazine-1-carbonyl)piperidine-1-carbonyl]thiophen-2-yl}-1H-indole
G125-0751 Screening compound: 2-methyl-1-{5-[4-(4-methylpiperazine-1-carbonyl)piperidine-1-carbonyl]thiophen-2-yl}-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound G125-0751
2-methyl-1-{5-[4-(4-methylpiperazine-1-carbonyl)piperidine-1-carbonyl]thiophen-2-yl}-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G125-0751

Molecular Formula

C25H30N4O2S (C25 H30 N4 O2 S)

Compound Name

2-methyl-1-{5-[4-(4-methylpiperazine-1-carbonyl)piperidine-1-carbonyl]thiophen-2-yl}-1H-indole

IUPAC name

2-methyl-1-{5-[4-(4-methylpiperazine-1-carbonyl)piperidine-1-carbonyl]thiophen-2-yl}-1H-indole

SMILES

Cc1cc(cccc2)c2n1-c1ccc(C(N(CC2)CCC2C(N2CCN(C)CC2)=O)=O)s1

InChI

InChI=1S/C25H30N4O2S/c1-18-17-20-5-3-4-6-21(20)29(18)23-8-7-22(32-23)25(31)27-11-9-19(10-12-27)24(30)28-15-13-26(2)14-16-28/h3-8,17,19H,9-16H2,1-2H3

InChI Key

MCNZIPQMHXAOEB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14982703

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

450.6

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.347

Distribution Coefficient, logD

2.999

Water Solubility, LogSw

-3.49

Polar Surface Area

40.549

Acid Dissociation Constant (pKa)

23.62

Base Dissociation Constant (pKb)

7.49

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.00

G125-0751 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anti-Inflammatory Library (24602 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G125-0751 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G125-0751?
Check Price and Availability of G125-0751, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G125-0751 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G125-0751
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G125-0751
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G125-0751 available by request