G141-0253 Screening compound: methyl 7-methyl-1-({[3-(methylsulfanyl)phenyl]carbamoyl}methyl)-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate

G141-0253 Screening compound: methyl 7-methyl-1-({[3-(methylsulfanyl)phenyl]carbamoyl}methyl)-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate
G141-0253 Screening compound: methyl 7-methyl-1-({[3-(methylsulfanyl)phenyl]carbamoyl}methyl)-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound G141-0253
methyl 7-methyl-1-({[3-(methylsulfanyl)phenyl]carbamoyl}methyl)-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G141-0253

Molecular Formula

C20H19N3O4S (C20 H19 N3 O4 S)

Compound Name

methyl 7-methyl-1-({[3-(methylsulfanyl)phenyl]carbamoyl}methyl)-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate

IUPAC name

methyl 7-methyl-1-({[3-(methylsulfanyl)phenyl]carbamoyl}methyl)-4-oxo-14-dihydro-18-naphthyridine-3-carboxylate

SMILES

Cc1ccc(C(C(C(OC)=O)=CN2CC(Nc3cccc(SC)c3)=O)=O)c2n1

InChI

InChI=1S/C20H19N3O4S/c1-12-7-8-15-18(25)16(20(26)27-2)10-23(19(15)21-12)11-17(24)22-13-5-4-6-14(9-13)28-3/h4-10H,11H2,1-3H3,(H,22,24)

InChI Key

VJFZFEWXMWJIDI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14982883

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

397.45

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.357

Distribution Coefficient, logD

3.357

Water Solubility, LogSw

-3.65

Polar Surface Area

69.591

Acid Dissociation Constant (pKa)

12.61

Base Dissociation Constant (pKb)

-0.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

G141-0253 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G141-0253 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G141-0253?
Check Price and Availability of G141-0253, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G141-0253 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G141-0253
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G141-0253
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G141-0253 available by request