G189-2181 Screening compound: ethyl 5-{3-[(3-chloro-4-methoxyphenyl)sulfamoyl]-4-methoxyphenyl}-1,2-oxazole-3-carboxylate

G189-2181 Screening compound: ethyl 5-{3-[(3-chloro-4-methoxyphenyl)sulfamoyl]-4-methoxyphenyl}-1,2-oxazole-3-carboxylate
G189-2181 Screening compound: ethyl 5-{3-[(3-chloro-4-methoxyphenyl)sulfamoyl]-4-methoxyphenyl}-1,2-oxazole-3-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound G189-2181
ethyl 5-{3-[(3-chloro-4-methoxyphenyl)sulfamoyl]-4-methoxyphenyl}-1,2-oxazole-3-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G189-2181

Molecular Formula

C20H19ClN2O7S (C20 H19 ClN2 O7 S)

Compound Name

ethyl 5-{3-[(3-chloro-4-methoxyphenyl)sulfamoyl]-4-methoxyphenyl}-1,2-oxazole-3-carboxylate

IUPAC name

ethyl 5-{3-[(3-chloro-4-methoxyphenyl)sulfamoyl]-4-methoxyphenyl}-12-oxazole-3-carboxylate

SMILES

CCOC(c1noc(-c(cc2)cc(S(Nc(cc3)cc(Cl)c3OC)(=O)=O)c2OC)c1)=O

InChI

InChI=1S/C20H19ClN2O7S/c1-4-29-20(24)15-11-18(30-22-15)12-5-7-17(28-3)19(9-12)31(25,26)23-13-6-8-16(27-2)14(21)10-13/h5-11,23H,4H2,1-3H3

InChI Key

JWGYGHCZGVHOAO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14982984

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

466.9

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.051

Distribution Coefficient, logD

2.918

Water Solubility, LogSw

-4.52

Polar Surface Area

98.438

Acid Dissociation Constant (pKa)

6.30

Base Dissociation Constant (pKb)

-7.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

G189-2181 in Drug Discovery

Included in Screening Libraries

Neuropeptide S Library (2850 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Nervous system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G189-2181 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G189-2181?
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What is the minimum amount of G189-2181 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G189-2181
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G189-2181
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G189-2181 available by request