G189-2200 Screening compound: ethyl 5-{4-methoxy-3-[(2-methyl-2,3-dihydro-1H-indol-1-yl)sulfonyl]phenyl}-1,2-oxazole-3-carboxylate

G189-2200 Screening compound: ethyl 5-{4-methoxy-3-[(2-methyl-2,3-dihydro-1H-indol-1-yl)sulfonyl]phenyl}-1,2-oxazole-3-carboxylate
G189-2200 Screening compound: ethyl 5-{4-methoxy-3-[(2-methyl-2,3-dihydro-1H-indol-1-yl)sulfonyl]phenyl}-1,2-oxazole-3-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound G189-2200
ethyl 5-{4-methoxy-3-[(2-methyl-2,3-dihydro-1H-indol-1-yl)sulfonyl]phenyl}-1,2-oxazole-3-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G189-2200

Molecular Formula

C22H22N2O6S (C22 H22 N2 O6 S)

Compound Name

ethyl 5-{4-methoxy-3-[(2-methyl-2,3-dihydro-1H-indol-1-yl)sulfonyl]phenyl}-1,2-oxazole-3-carboxylate

IUPAC name

ethyl 5-{4-methoxy-3-[(2-methyl-23-dihydro-1H-indol-1-yl)sulfonyl]phenyl}-12-oxazole-3-carboxylate

SMILES

CCOC(c1noc(-c(cc2)cc(S(N(C(C)C3)c4c3cccc4)(=O)=O)c2OC)c1)=O

InChI

InChI=1S/C22H22N2O6S/c1-4-29-22(25)17-13-20(30-23-17)16-9-10-19(28-3)21(12-16)31(26,27)24-14(2)11-15-7-5-6-8-18(15)24/h5-10,12-14H,4,11H2,1-3H3/t14-/m0/s1

InChI Key

HWWIYAADVHQWNJ-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD14982992

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

442.49

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.220

Distribution Coefficient, logD

4.220

Water Solubility, LogSw

-4.30

Polar Surface Area

81.392

Acid Dissociation Constant (pKa)

26.07

Base Dissociation Constant (pKb)

-7.91

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

27.30

G189-2200 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with G189-2200 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G189-2200?
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What is the minimum amount of G189-2200 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G189-2200
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G189-2200
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G189-2200 available by request