G189-2426 Screening compound: N-(4-methyl-1,3-thiazol-2-yl)-5-[4-methyl-3-(morpholine-4-sulfonyl)phenyl]-1,2-oxazole-3-carboxamide

G189-2426 Screening compound: N-(4-methyl-1,3-thiazol-2-yl)-5-[4-methyl-3-(morpholine-4-sulfonyl)phenyl]-1,2-oxazole-3-carboxamide
G189-2426 Screening compound: N-(4-methyl-1,3-thiazol-2-yl)-5-[4-methyl-3-(morpholine-4-sulfonyl)phenyl]-1,2-oxazole-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G189-2426
N-(4-methyl-1,3-thiazol-2-yl)-5-[4-methyl-3-(morpholine-4-sulfonyl)phenyl]-1,2-oxazole-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G189-2426

Molecular Formula

C19H20N4O5S2 (C19 H20 N4 O5 S2)

Compound Name

N-(4-methyl-1,3-thiazol-2-yl)-5-[4-methyl-3-(morpholine-4-sulfonyl)phenyl]-1,2-oxazole-3-carboxamide

IUPAC name

N-(4-methyl-13-thiazol-2-yl)-5-[4-methyl-3-(morpholine-4-sulfonyl)phenyl]-12-oxazole-3-carboxamide

SMILES

Cc1csc(NC(c2noc(-c3cc(S(N4CCOCC4)(=O)=O)c(C)cc3)c2)=O)n1

InChI

InChI=1S/C19H20N4O5S2/c1-12-3-4-14(9-17(12)30(25,26)23-5-7-27-8-6-23)16-10-15(22-28-16)18(24)21-19-20-13(2)11-29-19/h3-4,9-11H,5-8H2,1-2H3,(H,20,21,24)

InChI Key

XPYHCUKAAYTQQL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27209866

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

448.52

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.024

Distribution Coefficient, logD

3.013

Water Solubility, LogSw

-3.28

Polar Surface Area

94.337

Acid Dissociation Constant (pKa)

9.00

Base Dissociation Constant (pKb)

1.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.60

G189-2426 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G189-2426 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G189-2426?
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What is the minimum amount of G189-2426 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G189-2426
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G189-2426
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G189-2426 available by request