G193-0381 Screening compound: N-(3-{5-methyl-1-[4-(propan-2-yl)phenyl]-1H-1,2,3-triazol-4-yl}-1,2,4-thiadiazol-5-yl)thiophene-2-carboxamide

G193-0381 Screening compound: N-(3-{5-methyl-1-[4-(propan-2-yl)phenyl]-1H-1,2,3-triazol-4-yl}-1,2,4-thiadiazol-5-yl)thiophene-2-carboxamide
G193-0381 Screening compound: N-(3-{5-methyl-1-[4-(propan-2-yl)phenyl]-1H-1,2,3-triazol-4-yl}-1,2,4-thiadiazol-5-yl)thiophene-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G193-0381
N-(3-{5-methyl-1-[4-(propan-2-yl)phenyl]-1H-1,2,3-triazol-4-yl}-1,2,4-thiadiazol-5-yl)thiophene-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G193-0381

Molecular Formula

C19H18N6OS2 (C19 H18 N6 OS2)

Compound Name

N-(3-{5-methyl-1-[4-(propan-2-yl)phenyl]-1H-1,2,3-triazol-4-yl}-1,2,4-thiadiazol-5-yl)thiophene-2-carboxamide

IUPAC name

N-(3-{5-methyl-1-[4-(propan-2-yl)phenyl]-1H-123-triazol-4-yl}-124-thiadiazol-5-yl)thiophene-2-carboxamide

SMILES

CC(C)c(cc1)ccc1-n1nnc(-c2nsc(NC(c3cccs3)=O)n2)c1C

InChI

InChI=1S/C19H18N6OS2/c1-11(2)13-6-8-14(9-7-13)25-12(3)16(22-24-25)17-20-19(28-23-17)21-18(26)15-5-4-10-27-15/h4-11H,1-3H3,(H,20,21,23,26)

InChI Key

UMIHFFOEZIWPOT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14983253

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

410.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.782

Distribution Coefficient, logD

4.781

Water Solubility, LogSw

-4.47

Polar Surface Area

71.779

Acid Dissociation Constant (pKa)

10.32

Base Dissociation Constant (pKb)

2.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.10

G193-0381 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Therapeutical Diversity Annotated Library (7563 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G193-0381 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G193-0381?
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What is the minimum amount of G193-0381 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G193-0381
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G193-0381
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G193-0381 available by request