G194-0100 Screening compound: 3-{[(4-chlorophenyl)methyl]amino}-1-(3-fluorophenyl)-1,2-dihydropyrazin-2-one

G194-0100 Screening compound: 3-{[(4-chlorophenyl)methyl]amino}-1-(3-fluorophenyl)-1,2-dihydropyrazin-2-one
G194-0100 Screening compound: 3-{[(4-chlorophenyl)methyl]amino}-1-(3-fluorophenyl)-1,2-dihydropyrazin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G194-0100
3-{[(4-chlorophenyl)methyl]amino}-1-(3-fluorophenyl)-1,2-dihydropyrazin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G194-0100

Molecular Formula

C17H13ClFN3O (C17 H13 ClFN3 O)

Compound Name

3-{[(4-chlorophenyl)methyl]amino}-1-(3-fluorophenyl)-1,2-dihydropyrazin-2-one

IUPAC name

3-{[(4-chlorophenyl)methyl]amino}-1-(3-fluorophenyl)-12-dihydropyrazin-2-one

SMILES

O=C(C(NCc(cc1)ccc1Cl)=NC=C1)N1c1cc(F)ccc1

InChI

InChI=1S/C17H13ClFN3O/c18-13-6-4-12(5-7-13)11-21-16-17(23)22(9-8-20-16)15-3-1-2-14(19)10-15/h1-10H,11H2,(H,20,21)

InChI Key

JHLWICXQUWOPLA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14983525

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

329.76

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

2.348

Distribution Coefficient, logD

2.347

Water Solubility, LogSw

-3.41

Polar Surface Area

35.301

Acid Dissociation Constant (pKa)

10.04

Base Dissociation Constant (pKb)

1.36

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.90

G194-0100 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Mechanism of action:
  • Epigenetic
  • Receptor's ligands
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G194-0100 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G194-0100?
Check Price and Availability of G194-0100, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G194-0100 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G194-0100
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G194-0100
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G194-0100 available by request