G194-0105 Screening compound: 3-{[2-(4-CHLOROPHENYL)ETHYL]AMINO}-1-(3-FLUOROPHENYL)-1,2-DIHYDROPYRAZIN-2-ONE

G194-0105 Screening compound: 3-{[2-(4-CHLOROPHENYL)ETHYL]AMINO}-1-(3-FLUOROPHENYL)-1,2-DIHYDROPYRAZIN-2-ONE
G194-0105 Screening compound: 3-{[2-(4-CHLOROPHENYL)ETHYL]AMINO}-1-(3-FLUOROPHENYL)-1,2-DIHYDROPYRAZIN-2-ONE alternative view

Chemical Structure Depiction of ChemDiv screening compound G194-0105
3-{[2-(4-CHLOROPHENYL)ETHYL]AMINO}-1-(3-FLUOROPHENYL)-1,2-DIHYDROPYRAZIN-2-ONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G194-0105

Molecular Formula

C18H15ClFN3O (C18 H15 ClFN3 O)

Compound Name

3-{[2-(4-CHLOROPHENYL)ETHYL]AMINO}-1-(3-FLUOROPHENYL)-1,2-DIHYDROPYRAZIN-2-ONE

IUPAC name

n/a

SMILES

O=C(C(NCCc(cc1)ccc1Cl)=NC=C1)N1c1cc(F)ccc1

InChI

InChI=1S/C18H15ClFN3O/c19-14-6-4-13(5-7-14)8-9-21-17-18(24)23(11-10-22-17)16-3-1-2-15(20)12-16/h1-7,10-12H,8-9H2,(H,21,22)

InChI Key

CEOBCSCWBQVRTP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14983527

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

343.79

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

2.513

Distribution Coefficient, logD

2.513

Water Solubility, LogSw

-3.47

Polar Surface Area

35.143

Acid Dissociation Constant (pKa)

11.83

Base Dissociation Constant (pKb)

2.92

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

G194-0105 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

C-Met Library (15277 compounds)

Immunological Library (6760 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Mechanism of action:
  • Epigenetic
  • Receptor's ligands
Targets:
  • Kinases
  • Others

References: we are preparing a list of scientific research reports with G194-0105 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G194-0105?
Check Price and Availability of G194-0105, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G194-0105 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G194-0105
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G194-0105
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G194-0105 available by request