G194-0520 Screening compound: 3-{[(4-fluorophenyl)methyl]amino}-1-(2-methoxyphenyl)-1,2-dihydropyrazin-2-one

G194-0520 Screening compound: 3-{[(4-fluorophenyl)methyl]amino}-1-(2-methoxyphenyl)-1,2-dihydropyrazin-2-one
G194-0520 Screening compound: 3-{[(4-fluorophenyl)methyl]amino}-1-(2-methoxyphenyl)-1,2-dihydropyrazin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G194-0520
3-{[(4-fluorophenyl)methyl]amino}-1-(2-methoxyphenyl)-1,2-dihydropyrazin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G194-0520

Molecular Formula

C18H16FN3O2 (C18 H16 FN3 O2)

Compound Name

3-{[(4-fluorophenyl)methyl]amino}-1-(2-methoxyphenyl)-1,2-dihydropyrazin-2-one

IUPAC name

3-{[(4-fluorophenyl)methyl]amino}-1-(2-methoxyphenyl)-12-dihydropyrazin-2-one

SMILES

COc(cccc1)c1N(C=CN=C1NCc(cc2)ccc2F)C1=O

InChI

InChI=1S/C18H16FN3O2/c1-24-16-5-3-2-4-15(16)22-11-10-20-17(18(22)23)21-12-13-6-8-14(19)9-7-13/h2-11H,12H2,1H3,(H,20,21)

InChI Key

BADGEPKYCFKOLA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14983745

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

325.34

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.597

Distribution Coefficient, logD

1.597

Water Solubility, LogSw

-1.86

Polar Surface Area

42.631

Acid Dissociation Constant (pKa)

10.34

Base Dissociation Constant (pKb)

-6.86

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

G194-0520 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G194-0520 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G194-0520?
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What is the minimum amount of G194-0520 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G194-0520
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G194-0520
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G194-0520 available by request