G196-1375 Screening compound: 2-[5-amino-4-(4-fluorobenzenesulfonyl)-3-(methylsulfanyl)-1H-pyrazol-1-yl]-N-(2,5-difluorophenyl)acetamide

G196-1375 Screening compound: 2-[5-amino-4-(4-fluorobenzenesulfonyl)-3-(methylsulfanyl)-1H-pyrazol-1-yl]-N-(2,5-difluorophenyl)acetamide
G196-1375 Screening compound: 2-[5-amino-4-(4-fluorobenzenesulfonyl)-3-(methylsulfanyl)-1H-pyrazol-1-yl]-N-(2,5-difluorophenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G196-1375
2-[5-amino-4-(4-fluorobenzenesulfonyl)-3-(methylsulfanyl)-1H-pyrazol-1-yl]-N-(2,5-difluorophenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G196-1375

Molecular Formula

C18H15F3N4O3S2 (C18 H15 F3 N4 O3 S2)

Compound Name

2-[5-amino-4-(4-fluorobenzenesulfonyl)-3-(methylsulfanyl)-1H-pyrazol-1-yl]-N-(2,5-difluorophenyl)acetamide

IUPAC name

2-[5-amino-4-(4-fluorobenzenesulfonyl)-3-(methylsulfanyl)-1H-pyrazol-1-yl]-N-(25-difluorophenyl)acetamide

SMILES

CSc1nn(CC(Nc(cc(cc2)F)c2F)=O)c(N)c1S(c(cc1)ccc1F)(=O)=O

InChI

InChI=1S/C18H15F3N4O3S2/c1-29-18-16(30(27,28)12-5-2-10(19)3-6-12)17(22)25(24-18)9-15(26)23-14-8-11(20)4-7-13(14)21/h2-8H,9,22H2,1H3,(H,23,26)

InChI Key

BHCYFIIJCNKHPV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27210167

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

456.47

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.688

Distribution Coefficient, logD

2.676

Water Solubility, LogSw

-3.22

Polar Surface Area

85.278

Acid Dissociation Constant (pKa)

8.98

Base Dissociation Constant (pKb)

-0.79

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

G196-1375 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G196-1375 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G196-1375?
Check Price and Availability of G196-1375, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G196-1375 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G196-1375
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G196-1375
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G196-1375 available by request