G205-0285 Screening compound: 6-{4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazine-1-carbonyl}-2-(4-methylpiperidin-1-yl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one

G205-0285 Screening compound: 6-{4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazine-1-carbonyl}-2-(4-methylpiperidin-1-yl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one
G205-0285 Screening compound: 6-{4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazine-1-carbonyl}-2-(4-methylpiperidin-1-yl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G205-0285
6-{4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazine-1-carbonyl}-2-(4-methylpiperidin-1-yl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G205-0285

Molecular Formula

C24H28N6O4S (C24 H28 N6 O4 S)

Compound Name

6-{4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazine-1-carbonyl}-2-(4-methylpiperidin-1-yl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one

IUPAC name

6-{4-[(2H-13-benzodioxol-5-yl)methyl]piperazine-1-carbonyl}-2-(4-methylpiperidin-1-yl)-5H-[134]thiadiazolo[32-a]pyrimidin-5-one

SMILES

CC(CC1)CCN1C(SC1=NC=C2C(N3CCN(Cc(cc4)cc5c4OCO5)CC3)=O)=NN1C2=O

InChI

InChI=1S/C24H28N6O4S/c1-16-4-6-29(7-5-16)24-26-30-22(32)18(13-25-23(30)35-24)21(31)28-10-8-27(9-11-28)14-17-2-3-19-20(12-17)34-15-33-19/h2-3,12-13,16H,4-11,14-15H2,1H3

InChI Key

JYDHLVXHRBMBKQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14985307

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

496.59

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.220

Distribution Coefficient, logD

1.978

Water Solubility, LogSw

-2.78

Polar Surface Area

78.131

Acid Dissociation Constant (pKa)

26.31

Base Dissociation Constant (pKb)

7.27

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

G205-0285 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

RNA-Protein Interaction Inhibitors Library (1986 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Others
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G205-0285 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G205-0285?
Check Price and Availability of G205-0285, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G205-0285 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G205-0285
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G205-0285
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G205-0285 available by request