G205-2167 Screening compound: 2-(diethylamino)-N-{[4-(methylsulfanyl)phenyl]methyl}-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidine-6-carboxamide

G205-2167 Screening compound: 2-(diethylamino)-N-{[4-(methylsulfanyl)phenyl]methyl}-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidine-6-carboxamide
G205-2167 Screening compound: 2-(diethylamino)-N-{[4-(methylsulfanyl)phenyl]methyl}-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G205-2167
2-(diethylamino)-N-{[4-(methylsulfanyl)phenyl]methyl}-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G205-2167

Molecular Formula

C18H21N5O2S2 (C18 H21 N5 O2 S2)

Compound Name

2-(diethylamino)-N-{[4-(methylsulfanyl)phenyl]methyl}-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidine-6-carboxamide

IUPAC name

2-(diethylamino)-N-{[4-(methylsulfanyl)phenyl]methyl}-5-oxo-5H-[134]thiadiazolo[32-a]pyrimidine-6-carboxamide

SMILES

CCN(CC)C(SC1=NC=C2C(NCc(cc3)ccc3SC)=O)=NN1C2=O

InChI

InChI=1S/C18H21N5O2S2/c1-4-22(5-2)18-21-23-16(25)14(11-20-17(23)27-18)15(24)19-10-12-6-8-13(26-3)9-7-12/h6-9,11H,4-5,10H2,1-3H3,(H,19,24)

InChI Key

YERDNCMKIFONMO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14985669

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

403.53

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.589

Distribution Coefficient, logD

2.462

Water Solubility, LogSw

-2.84

Polar Surface Area

64.524

Acid Dissociation Constant (pKa)

7.89

Base Dissociation Constant (pKb)

5.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

G205-2167 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with G205-2167 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G205-2167?
Check Price and Availability of G205-2167, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G205-2167 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G205-2167
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G205-2167
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G205-2167 available by request