G207-0006 Screening compound: 1-[5-(3,4-dimethylphenyl)-4-methyl-1,1-dioxo-1H-1lambda~6~-isothiazol-3-yl]-N~4~-(3-pyridylmethyl)-4-piperidinecarboxamide

G207-0006 Screening compound: 1-[5-(3,4-dimethylphenyl)-4-methyl-1,1-dioxo-1H-1lambda~6~-isothiazol-3-yl]-N~4~-(3-pyridylmethyl)-4-piperidinecarboxamide
G207-0006 Screening compound: 1-[5-(3,4-dimethylphenyl)-4-methyl-1,1-dioxo-1H-1lambda~6~-isothiazol-3-yl]-N~4~-(3-pyridylmethyl)-4-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G207-0006
1-[5-(3,4-dimethylphenyl)-4-methyl-1,1-dioxo-1H-1lambda~6~-isothiazol-3-yl]-N~4~-(3-pyridylmethyl)-4-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G207-0006

Molecular Formula

C24H28N4O3S (C24 H28 N4 O3 S)

Compound Name

1-[5-(3,4-dimethylphenyl)-4-methyl-1,1-dioxo-1H-1lambda~6~-isothiazol-3-yl]-N~4~-(3-pyridylmethyl)-4-piperidinecarboxamide

IUPAC name

1-[5-(34-dimethylphenyl)-4-methyl-11-dioxo-1lambda62-thiazol-3-yl]-N-[(pyridin-3-yl)methyl]piperidine-4-carboxamide

SMILES

CC(C(N(CC1)CCC1C(NCc1cnccc1)=O)=N1)=C(c2cc(C)c(C)cc2)S1(=O)=O

InChI

InChI=1S/C24H28N4O3S/c1-16-6-7-21(13-17(16)2)22-18(3)23(27-32(22,30)31)28-11-8-20(9-12-28)24(29)26-15-19-5-4-10-25-14-19/h4-7,10,13-14,20H,8-9,11-12,15H2,1-3H3,(H,26,29)

InChI Key

GJOBKMFZURKTPZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14985910

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

452.58

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.639

Distribution Coefficient, logD

2.636

Water Solubility, LogSw

-2.72

Polar Surface Area

77.061

Acid Dissociation Constant (pKa)

13.36

Base Dissociation Constant (pKb)

5.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

G207-0006 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G207-0006 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G207-0006?
Check Price and Availability of G207-0006, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G207-0006 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G207-0006
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G207-0006
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G207-0006 available by request