G210-1517 Screening compound: N-[(4-chlorophenyl)methyl]-3-(4-fluorophenyl)-2,7-dimethylpyrazolo[1,5-a]pyrimidine-6-carboxamide

G210-1517 Screening compound: N-[(4-chlorophenyl)methyl]-3-(4-fluorophenyl)-2,7-dimethylpyrazolo[1,5-a]pyrimidine-6-carboxamide
G210-1517 Screening compound: N-[(4-chlorophenyl)methyl]-3-(4-fluorophenyl)-2,7-dimethylpyrazolo[1,5-a]pyrimidine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G210-1517
N-[(4-chlorophenyl)methyl]-3-(4-fluorophenyl)-2,7-dimethylpyrazolo[1,5-a]pyrimidine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G210-1517

Molecular Formula

C22H18ClFN4O (C22 H18 ClFN4 O)

Compound Name

N-[(4-chlorophenyl)methyl]-3-(4-fluorophenyl)-2,7-dimethylpyrazolo[1,5-a]pyrimidine-6-carboxamide

IUPAC name

N-[(4-chlorophenyl)methyl]-3-(4-fluorophenyl)-27-dimethylpyrazolo[15-a]pyrimidine-6-carboxamide

SMILES

Cc(c(-c(cc1)ccc1F)c1nc2)nn1c(C)c2C(NCc(cc1)ccc1Cl)=O

InChI

InChI=1S/C22H18ClFN4O/c1-13-20(16-5-9-18(24)10-6-16)21-25-12-19(14(2)28(21)27-13)22(29)26-11-15-3-7-17(23)8-4-15/h3-10,12H,11H2,1-2H3,(H,26,29)

InChI Key

ROTKUDXTNQCYOE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14986471

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

408.86

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.020

Distribution Coefficient, logD

4.020

Water Solubility, LogSw

-4.81

Polar Surface Area

45.202

Acid Dissociation Constant (pKa)

11.01

Base Dissociation Constant (pKb)

3.02

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

G210-1517 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G210-1517 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G210-1517?
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What is the minimum amount of G210-1517 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G210-1517
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G210-1517
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G210-1517 available by request