G211-0075 Screening compound: 2-cyclohexyl-9-[4-(4-fluorophenyl)piperazine-1-carbonyl]-1H,2H,3H-pyrrolo[3,4-b]quinolin-3-one

G211-0075 Screening compound: 2-cyclohexyl-9-[4-(4-fluorophenyl)piperazine-1-carbonyl]-1H,2H,3H-pyrrolo[3,4-b]quinolin-3-one
G211-0075 Screening compound: 2-cyclohexyl-9-[4-(4-fluorophenyl)piperazine-1-carbonyl]-1H,2H,3H-pyrrolo[3,4-b]quinolin-3-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G211-0075
2-cyclohexyl-9-[4-(4-fluorophenyl)piperazine-1-carbonyl]-1H,2H,3H-pyrrolo[3,4-b]quinolin-3-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G211-0075

Molecular Formula

C28H29FN4O2 (C28 H29 FN4 O2)

Compound Name

2-cyclohexyl-9-[4-(4-fluorophenyl)piperazine-1-carbonyl]-1H,2H,3H-pyrrolo[3,4-b]quinolin-3-one

IUPAC name

2-cyclohexyl-9-[4-(4-fluorophenyl)piperazine-1-carbonyl]-1H2H3H-pyrrolo[34-b]quinolin-3-one

SMILES

O=C(c1c(CN(C2CCCCC2)C2=O)c2nc2ccccc12)N(CC1)CCN1c(cc1)ccc1F

InChI

InChI=1S/C28H29FN4O2/c29-19-10-12-20(13-11-19)31-14-16-32(17-15-31)27(34)25-22-8-4-5-9-24(22)30-26-23(25)18-33(28(26)35)21-6-2-1-3-7-21/h4-5,8-13,21H,1-3,6-7,14-18H2

InChI Key

XSUCYFGGUYHWFL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14986690

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

472.56

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.752

Distribution Coefficient, logD

4.752

Water Solubility, LogSw

-4.94

Polar Surface Area

45.373

Acid Dissociation Constant (pKa)

17.38

Base Dissociation Constant (pKb)

1.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.30

G211-0075 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Anticancer Library (62698 compounds)

Antimitotic Tubulin Library (17355 compounds)

Antiviral Library (67538 compounds)

CNS targets activity set (6557 compounds)

GABA Library (7115 compounds)

Human GPCR Annotated Library (5539 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Mimetics
Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Antiviral
  • Infections
  • Immune system
  • Eye
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • PPI modulators

References: we are preparing a list of scientific research reports with G211-0075 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G211-0075?
Check Price and Availability of G211-0075, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G211-0075 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G211-0075
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G211-0075
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G211-0075 available by request