G217-0167 Screening compound: N-(4-{[2-(4-ETHYLPIPERAZIN-1-YL)ETHYL]CARBAMOYL}PHENYL)-2,3,4,5-TETRAHYDRO-1H-1-BENZAZEPINE-1-CARBOXAMIDE

G217-0167 Screening compound: N-(4-{[2-(4-ETHYLPIPERAZIN-1-YL)ETHYL]CARBAMOYL}PHENYL)-2,3,4,5-TETRAHYDRO-1H-1-BENZAZEPINE-1-CARBOXAMIDE
G217-0167 Screening compound: N-(4-{[2-(4-ETHYLPIPERAZIN-1-YL)ETHYL]CARBAMOYL}PHENYL)-2,3,4,5-TETRAHYDRO-1H-1-BENZAZEPINE-1-CARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound G217-0167
N-(4-{[2-(4-ETHYLPIPERAZIN-1-YL)ETHYL]CARBAMOYL}PHENYL)-2,3,4,5-TETRAHYDRO-1H-1-BENZAZEPINE-1-CARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G217-0167

Molecular Formula

C26H35N5O2 (C26 H35 N5 O2)

Compound Name

N-(4-{[2-(4-ETHYLPIPERAZIN-1-YL)ETHYL]CARBAMOYL}PHENYL)-2,3,4,5-TETRAHYDRO-1H-1-BENZAZEPINE-1-CARBOXAMIDE

IUPAC name

n/a

SMILES

CCN1CCN(CCNC(c(cc2)ccc2NC(N(CCCC2)c3c2cccc3)=O)=O)CC1

InChI

InChI=1S/C26H35N5O2/c1-2-29-17-19-30(20-18-29)16-14-27-25(32)22-10-12-23(13-11-22)28-26(33)31-15-6-5-8-21-7-3-4-9-24(21)31/h3-4,7,9-13H,2,5-6,8,14-20H2,1H3,(H,27,32)(H,28,33)

InChI Key

LMIIODLKHIBKNY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14987339

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

449.6

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.193

Distribution Coefficient, logD

2.400

Water Solubility, LogSw

-3.50

Polar Surface Area

56.477

Acid Dissociation Constant (pKa)

11.11

Base Dissociation Constant (pKb)

8.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

46.20

G217-0167 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with G217-0167 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G217-0167?
Check Price and Availability of G217-0167, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G217-0167 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G217-0167
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G217-0167
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G217-0167 available by request