G219-0367 Screening compound: 2-{[1-(3-chloro-2-methylphenyl)-3,4-dimethyl-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}-N-(propan-2-yl)acetamide

G219-0367 Screening compound: 2-{[1-(3-chloro-2-methylphenyl)-3,4-dimethyl-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}-N-(propan-2-yl)acetamide
G219-0367 Screening compound: 2-{[1-(3-chloro-2-methylphenyl)-3,4-dimethyl-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}-N-(propan-2-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G219-0367
2-{[1-(3-chloro-2-methylphenyl)-3,4-dimethyl-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}-N-(propan-2-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G219-0367

Molecular Formula

C20H23ClN4O2 (C20 H23 ClN4 O2)

Compound Name

2-{[1-(3-chloro-2-methylphenyl)-3,4-dimethyl-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}-N-(propan-2-yl)acetamide

IUPAC name

2-{[1-(3-chloro-2-methylphenyl)-34-dimethyl-1H-pyrazolo[34-b]pyridin-6-yl]oxy}-N-(propan-2-yl)acetamide

SMILES

CC(C)NC(COc1cc(C)c(c(C)nn2-c3cccc(Cl)c3C)c2n1)=O

InChI

InChI=1S/C20H23ClN4O2/c1-11(2)22-17(26)10-27-18-9-12(3)19-14(5)24-25(20(19)23-18)16-8-6-7-15(21)13(16)4/h6-9,11H,10H2,1-5H3,(H,22,26)

InChI Key

BNARRZLKEGNADX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27211081

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

386.88

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.301

Distribution Coefficient, logD

4.301

Water Solubility, LogSw

-4.50

Polar Surface Area

54.178

Acid Dissociation Constant (pKa)

15.57

Base Dissociation Constant (pKb)

5.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.00

G219-0367 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with G219-0367 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G219-0367?
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What is the minimum amount of G219-0367 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G219-0367
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G219-0367
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G219-0367 available by request