G219-4027 Screening compound: 1-(2,3-dihydro-1H-indol-1-yl)-2-{[1-(4-ethylphenyl)-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}ethan-1-one

G219-4027 Screening compound: 1-(2,3-dihydro-1H-indol-1-yl)-2-{[1-(4-ethylphenyl)-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}ethan-1-one
G219-4027 Screening compound: 1-(2,3-dihydro-1H-indol-1-yl)-2-{[1-(4-ethylphenyl)-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G219-4027
1-(2,3-dihydro-1H-indol-1-yl)-2-{[1-(4-ethylphenyl)-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G219-4027

Molecular Formula

C26H23F3N4O2 (C26 H23 F3 N4 O2)

Compound Name

1-(2,3-dihydro-1H-indol-1-yl)-2-{[1-(4-ethylphenyl)-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}ethan-1-one

IUPAC name

1-(23-dihydro-1H-indol-1-yl)-2-{[1-(4-ethylphenyl)-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[34-b]pyridin-6-yl]oxy}ethan-1-one

SMILES

CCc(cc1)ccc1-n(c1n2)nc(C)c1c(C(F)(F)F)cc2OCC(N(CC1)c2c1cccc2)=O

InChI

InChI=1S/C26H23F3N4O2/c1-3-17-8-10-19(11-9-17)33-25-24(16(2)31-33)20(26(27,28)29)14-22(30-25)35-15-23(34)32-13-12-18-6-4-5-7-21(18)32/h4-11,14H,3,12-13,15H2,1-2H3

InChI Key

SSXDJKJPGNSCDU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27211332

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

480.49

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.862

Distribution Coefficient, logD

5.862

Water Solubility, LogSw

-5.73

Polar Surface Area

46.185

Acid Dissociation Constant (pKa)

18.84

Base Dissociation Constant (pKb)

1.97

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.90

G219-4027 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with G219-4027 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G219-4027?
Check Price and Availability of G219-4027, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G219-4027 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G219-4027
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G219-4027
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G219-4027 available by request