G219-4160 Screening compound: 2-{[1,3-dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}-N-(2-fluorophenyl)acetamide

G219-4160 Screening compound: 2-{[1,3-dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}-N-(2-fluorophenyl)acetamide
G219-4160 Screening compound: 2-{[1,3-dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}-N-(2-fluorophenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G219-4160
2-{[1,3-dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}-N-(2-fluorophenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G219-4160

Molecular Formula

C17H14F4N4O2 (C17 H14 F4 N4 O2)

Compound Name

2-{[1,3-dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}-N-(2-fluorophenyl)acetamide

IUPAC name

2-{[13-dimethyl-4-(trifluoromethyl)-1H-pyrazolo[34-b]pyridin-6-yl]oxy}-N-(2-fluorophenyl)acetamide

SMILES

Cc1nn(C)c2c1c(C(F)(F)F)cc(OCC(Nc(cccc1)c1F)=O)n2

InChI

InChI=1S/C17H14F4N4O2/c1-9-15-10(17(19,20)21)7-14(23-16(15)25(2)24-9)27-8-13(26)22-12-6-4-3-5-11(12)18/h3-7H,8H2,1-2H3,(H,22,26)

InChI Key

KMZOAJIHAOCPRO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27211368

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.32

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.045

Distribution Coefficient, logD

3.045

Water Solubility, LogSw

-3.62

Polar Surface Area

53.635

Acid Dissociation Constant (pKa)

10.86

Base Dissociation Constant (pKb)

-0.41

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.53

G219-4160 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G219-4160 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G219-4160?
Check Price and Availability of G219-4160, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G219-4160 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G219-4160
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G219-4160
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G219-4160 available by request