G219-6157 Screening compound: N-(5-chloro-2,4-dimethoxyphenyl)-2-{[1,3-dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}propanamide

G219-6157 Screening compound: N-(5-chloro-2,4-dimethoxyphenyl)-2-{[1,3-dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}propanamide
G219-6157 Screening compound: N-(5-chloro-2,4-dimethoxyphenyl)-2-{[1,3-dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G219-6157
N-(5-chloro-2,4-dimethoxyphenyl)-2-{[1,3-dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G219-6157

Molecular Formula

C20H20ClF3N4O4 (C20 H20 ClF3 N4 O4)

Compound Name

N-(5-chloro-2,4-dimethoxyphenyl)-2-{[1,3-dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}propanamide

IUPAC name

N-(5-chloro-24-dimethoxyphenyl)-2-{[13-dimethyl-4-(trifluoromethyl)-1H-pyrazolo[34-b]pyridin-6-yl]oxy}propanamide

SMILES

CC(C(Nc(c(OC)c1)cc(Cl)c1OC)=O)Oc1nc(n(C)nc2C)c2c(C(F)(F)F)c1

InChI

InChI=1S/C20H20ClF3N4O4/c1-9-17-11(20(22,23)24)6-16(26-18(17)28(3)27-9)32-10(2)19(29)25-13-7-12(21)14(30-4)8-15(13)31-5/h6-8,10H,1-5H3,(H,25,29)/t10-/m0/s1

InChI Key

AGNODWAVRCUXLW-JTQLQIEISA-N

MDL Number (MFCD)

MFCD27211577

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

472.85

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.977

Distribution Coefficient, logD

3.961

Water Solubility, LogSw

-4.27

Polar Surface Area

68.399

Acid Dissociation Constant (pKa)

8.84

Base Dissociation Constant (pKb)

1.35

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

35.00

G219-6157 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G219-6157 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G219-6157?
Check Price and Availability of G219-6157, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G219-6157 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G219-6157
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G219-6157
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G219-6157 available by request