G219-6185 Screening compound: 2-{[1,3-dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}-N-(2-fluorophenyl)propanamide

G219-6185 Screening compound: 2-{[1,3-dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}-N-(2-fluorophenyl)propanamide
G219-6185 Screening compound: 2-{[1,3-dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}-N-(2-fluorophenyl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G219-6185
2-{[1,3-dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}-N-(2-fluorophenyl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G219-6185

Molecular Formula

C18H16F4N4O2 (C18 H16 F4 N4 O2)

Compound Name

2-{[1,3-dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}-N-(2-fluorophenyl)propanamide

IUPAC name

2-{[13-dimethyl-4-(trifluoromethyl)-1H-pyrazolo[34-b]pyridin-6-yl]oxy}-N-(2-fluorophenyl)propanamide

SMILES

CC(C(Nc(cccc1)c1F)=O)Oc1nc(n(C)nc2C)c2c(C(F)(F)F)c1

InChI

InChI=1S/C18H16F4N4O2/c1-9-15-11(18(20,21)22)8-14(24-16(15)26(3)25-9)28-10(2)17(27)23-13-7-5-4-6-12(13)19/h4-8,10H,1-3H3,(H,23,27)/t10-/m0/s1

InChI Key

CQKDOEOIRCRKNH-JTQLQIEISA-N

MDL Number (MFCD)

MFCD27211602

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

396.34

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.458

Distribution Coefficient, logD

3.458

Water Solubility, LogSw

-4.16

Polar Surface Area

53.138

Acid Dissociation Constant (pKa)

10.61

Base Dissociation Constant (pKb)

-0.38

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

27.80

G219-6185 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G219-6185 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G219-6185?
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What is the minimum amount of G219-6185 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G219-6185
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G219-6185
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G219-6185 available by request