G221-0059 Screening compound: 2-[(4-fluorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-1,2,3,4-tetrahydroisoquinoline

G221-0059 Screening compound: 2-[(4-fluorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-1,2,3,4-tetrahydroisoquinoline
G221-0059 Screening compound: 2-[(4-fluorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-1,2,3,4-tetrahydroisoquinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound G221-0059
2-[(4-fluorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-1,2,3,4-tetrahydroisoquinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G221-0059

Molecular Formula

C24H20FN3O (C24 H20 FN3 O)

Compound Name

2-[(4-fluorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-1,2,3,4-tetrahydroisoquinoline

IUPAC name

2-[(4-fluorophenyl)(5-phenyl-134-oxadiazol-2-yl)methyl]-1234-tetrahydroisoquinoline

SMILES

Fc1ccc(C(c2nnc(-c3ccccc3)o2)N(CC2)Cc3c2cccc3)cc1

InChI

InChI=1S/C24H20FN3O/c25-21-12-10-18(11-13-21)22(28-15-14-17-6-4-5-9-20(17)16-28)24-27-26-23(29-24)19-7-2-1-3-8-19/h1-13,22H,14-16H2/t22-/m1/s1

InChI Key

FZSGJQUYHFMYGO-JOCHJYFZSA-N

MDL Number (MFCD)

MFCD14988455

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

385.44

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.237

Distribution Coefficient, logD

5.237

Water Solubility, LogSw

-5.50

Polar Surface Area

33.169

Acid Dissociation Constant (pKa)

24.92

Base Dissociation Constant (pKb)

3.01

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

16.70

G221-0059 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with G221-0059 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G221-0059?
Check Price and Availability of G221-0059, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G221-0059 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G221-0059
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G221-0059
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G221-0059 available by request