G221-0359 Screening compound: N-[(2-chloro-4-fluorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-2-ethylaniline

G221-0359 Screening compound: N-[(2-chloro-4-fluorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-2-ethylaniline
G221-0359 Screening compound: N-[(2-chloro-4-fluorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-2-ethylaniline alternative view

Chemical Structure Depiction of ChemDiv screening compound G221-0359
N-[(2-chloro-4-fluorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-2-ethylaniline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G221-0359

Molecular Formula

C23H19ClFN3O (C23 H19 ClFN3 O)

Compound Name

N-[(2-chloro-4-fluorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-2-ethylaniline

IUPAC name

N-[(2-chloro-4-fluorophenyl)(5-phenyl-134-oxadiazol-2-yl)methyl]-2-ethylaniline

SMILES

CCc(cccc1)c1NC(c1nnc(-c2ccccc2)o1)c(ccc(F)c1)c1Cl

InChI

InChI=1S/C23H19ClFN3O/c1-2-15-8-6-7-11-20(15)26-21(18-13-12-17(25)14-19(18)24)23-28-27-22(29-23)16-9-4-3-5-10-16/h3-14,21,26H,2H2,1H3/t21-/m1/s1

InChI Key

NCRCIIGNPCNJAK-OAQYLSRUSA-N

MDL Number (MFCD)

MFCD14988520

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

407.87

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.487

Distribution Coefficient, logD

6.487

Water Solubility, LogSw

-6.36

Polar Surface Area

39.371

Acid Dissociation Constant (pKa)

17.70

Base Dissociation Constant (pKb)

-2.23

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

13.00

G221-0359 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Agro:
  • Agro
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G221-0359 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G221-0359?
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What is the minimum amount of G221-0359 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G221-0359
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G221-0359
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G221-0359 available by request