G221-0781 Screening compound: N-(1,4-dimethyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)-4-(2-oxopyrrolidin-1-yl)benzene-1-sulfonamide

G221-0781 Screening compound: N-(1,4-dimethyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)-4-(2-oxopyrrolidin-1-yl)benzene-1-sulfonamide
G221-0781 Screening compound: N-(1,4-dimethyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)-4-(2-oxopyrrolidin-1-yl)benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G221-0781
N-(1,4-dimethyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)-4-(2-oxopyrrolidin-1-yl)benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G221-0781

Molecular Formula

C20H20N4O5S (C20 H20 N4 O5 S)

Compound Name

N-(1,4-dimethyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)-4-(2-oxopyrrolidin-1-yl)benzene-1-sulfonamide

IUPAC name

N-(14-dimethyl-23-dioxo-1234-tetrahydroquinoxalin-6-yl)-4-(2-oxopyrrolidin-1-yl)benzene-1-sulfonamide

SMILES

CN(c(ccc(NS(c(cc1)ccc1N(CCC1)C1=O)(=O)=O)c1)c1N(C)C1=O)C1=O

InChI

InChI=1S/C20H20N4O5S/c1-22-16-10-5-13(12-17(16)23(2)20(27)19(22)26)21-30(28,29)15-8-6-14(7-9-15)24-11-3-4-18(24)25/h5-10,12,21H,3-4,11H2,1-2H3

InChI Key

MPGYTGZXRALLFP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14988623

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.47

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

0.961

Distribution Coefficient, logD

0.944

Water Solubility, LogSw

-2.51

Polar Surface Area

88.064

Acid Dissociation Constant (pKa)

8.80

Base Dissociation Constant (pKb)

-0.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

G221-0781 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with G221-0781 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G221-0781?
Check Price and Availability of G221-0781, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G221-0781 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G221-0781
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G221-0781
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G221-0781 available by request