G221-0865 Screening compound: 4-bromo-N-[1,4-dimethyl-7-(morpholin-4-yl)-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl]benzene-1-sulfonamide

G221-0865 Screening compound: 4-bromo-N-[1,4-dimethyl-7-(morpholin-4-yl)-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl]benzene-1-sulfonamide
G221-0865 Screening compound: 4-bromo-N-[1,4-dimethyl-7-(morpholin-4-yl)-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl]benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G221-0865
4-bromo-N-[1,4-dimethyl-7-(morpholin-4-yl)-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl]benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G221-0865

Molecular Formula

C20H21BrN4O5S (C20 H21 BrN4 O5 S)

Compound Name

4-bromo-N-[1,4-dimethyl-7-(morpholin-4-yl)-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl]benzene-1-sulfonamide

IUPAC name

4-bromo-N-[14-dimethyl-7-(morpholin-4-yl)-23-dioxo-1234-tetrahydroquinoxalin-6-yl]benzene-1-sulfonamide

SMILES

CN(c(c(N(C)C1=O)c2)cc(NS(c(cc3)ccc3Br)(=O)=O)c2N2CCOCC2)C1=O

InChI

InChI=1S/C20H21BrN4O5S/c1-23-17-11-15(22-31(28,29)14-5-3-13(21)4-6-14)16(25-7-9-30-10-8-25)12-18(17)24(2)20(27)19(23)26/h3-6,11-12,22H,7-10H2,1-2H3

InChI Key

KCDSYDLILNPBCN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14988658

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

509.38

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.139

Distribution Coefficient, logD

-0.607

Water Solubility, LogSw

-3.00

Polar Surface Area

81.610

Acid Dissociation Constant (pKa)

4.65

Base Dissociation Constant (pKb)

0.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.00

G221-0865 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Antiviral Annotated Library (21441 compounds)

Antiviral Library (67538 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with G221-0865 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G221-0865?
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What is the minimum amount of G221-0865 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G221-0865
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G221-0865
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G221-0865 available by request